概述

  • 产品名称
    Anti-TMPRSS4抗体
    参阅全部 TMPRSS4 一抗
  • 描述
    山羊多克隆抗体to TMPRSS4
  • 特异性
    ab82176 is expected to recognize both reported isoforms (NP_063947.1 and NP_001077416.1).
  • 经测试应用
    适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse
  • 免疫原

    Synthetic peptide:

    DSTRCNADDAYQGE

    , corresponding to internal sequence amino acids 352-365 of Human TMPRSS4 (NP_063947.1) (or aa347-360 of NP_001077416.1).

  • 阳性对照
    • Human Bone Marrow lysate.

性能

应用

Our Abpromise guarantee covers the use of ab82176 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 - 3 µg/ml. Predicted molecular weight: 48 kDa.

靶标

  • 功能
    Probable protease. Seems to be capable of activating ENaC.
  • 组织特异性
    High levels in pancreatic, gastric, colorectal and ampullary cancer. Very weak expression in normal gastrointestinal and urogenital tract.
  • 序列相似性
    Belongs to the peptidase S1 family.
    Contains 1 LDL-receptor class A domain.
    Contains 1 peptidase S1 domain.
    Contains 1 SRCR domain.
  • 细胞定位
    Membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • UNQ776/PRO1570 antibody
    • CAPH2 antibody
    • Channel-activating protease 2 antibody
    • Membrane type serine protease 2 antibody
    • Membrane-type serine protease 2 antibody
    • MT SP2 antibody
    • MT-SP2 antibody
    • TMPRSS 4 antibody
    • TMPRSS3 antibody
    • TMPRSS4 antibody
    • TMPS4_HUMAN antibody
    • Transmembrane protease serine 4 antibody
    • Transmembrane protease, serine 4 antibody
    • Transmembrane serine protease 3 antibody
    see all

图片

  • Anti-TMPRSS4 antibody (ab82176) at 1 µg/ml + Human Bone Marrow lysate (in RIPA buffer) at 35 µg
    Developed using the ECL technique

    Predicted band size : 48 kDa
    Observed band size : 48 kDa

实验方案

文献

This product has been referenced in:
  • Li XM  et al. Overexpression of TMPRSS4 promotes tumor proliferation and aggressiveness in breast cancer. Int J Mol Med 39:927-935 (2017). Read more (PubMed: 28259959) »

See 1 Publication for this product

客户评价及客户问答

There are currently no Customer reviews or Questions for ab82176.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

注册