Multiple isoforms of TMEM59 are known to exist. This antibody is predicted to not cross-react with other TMEM family members.
A 16 amino acid peptide near amino terminus of Human TMEM59 (NP_004863)
Human Kidney Tissue Lysate
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Preservative: 0.02% Sodium Azide
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Immunogen affinity purified
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use a concentration of 20 µg/ml.
Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 36 kDa.
Use a concentration of 2.5 µg/ml.
Modulates the O-glycosylation and complex N-glycosylation steps occurring during the Golgi maturation of several proteins such as APP, BACE1, SEAP or PRNP. Inhibits APP transport to the cell surface and further shedding.
Belongs to the TMEM59 family.
Golgi apparatus membrane.
Information by UniProt
Liver membrane-bound protein antibody
Immunocytochemistry/ Immunofluorescence - Anti-TMEM59 antibody (ab105417)
Immunofluorescence of TMEM59 in Human kidney tissue with ab105417 at 20 ug/mL.
Western blot - TMEM59 antibody (ab105417)
All lanes : Anti-TMEM59 antibody (ab105417) at 1 µg/ml Lane 1 : Human kidney tissue lysate Lane 2 : Human kidney tissue lysate with blocking peptide Lysates/proteins at 15 µg per lane. Predicted band size : 36 kDa
Immunocytochemistry - Anti-TMEM59 antibody (ab105417)
Immunohistochemistry of TMEM59 in human kidney tissue with ab105417 at 2.5 µg/ml.
has not yet been referenced specifically in any publications.
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