概述

  • 产品名称Anti-TMEM49抗体
    参阅全部 TMEM49 一抗
  • 描述
    小鼠多克隆抗体to TMEM49
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Full length human protein

  • 阳性对照
    • TMEM49 transfected 293T lysate.

性能

应用

Our Abpromise guarantee covers the use of ab69224 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/1000. Detects a band of approximately 47 kDa (predicted molecular weight: 47 kDa).

靶标

  • 功能Stress-induced protein that, when overexpressed, promotes formation of intracellular vacuoles followed by cell death. May be involved in the cytoplasmic vacuolization of acinar cells during the early stage of acute pancreatitis. Plays a role in the initial stages of the autophagic process through its interaction with BECN1 (By similarity). Involved in cell-cell adhesion. Plays an essential role in formation of cell junctions.
  • 序列相似性Belongs to the VMP1 family.
  • 细胞定位Endoplasmic reticulum-Golgi intermediate compartment membrane. Cell membrane. Vacuole membrane. Endoplasmic reticulum.
  • Information by UniProt
  • 数据库链接
  • 别名
    • DKFZP566I133 antibody
    • ectopic P-granules autophagy protein 3 homolog antibody
    • NF E2 induceble protein 2 antibody
    • NF E2 inducible protein 2 antibody
    • ni 2 antibody
    • protein ni 2 antibody
    • Tango5 antibody
    • TDC1 antibody
    • TMEM49 antibody
    • Transmembrane protein 49 antibody
    • transport and golgi organization 5 homolog antibody
    • Vacuole membrane protein 1 antibody
    • vmp1 antibody
    • VMP1_HUMAN antibody
    see all

Anti-TMEM49 antibody 图像

  • All lanes : Anti-TMEM49 antibody (ab69224) at 1/500 dilution

    Lane 1 : TMEM49 transfected 293T lysate
    Lane 2 : Non-transfected 293T lysate

    Lysates/proteins at 25 µg per lane.

    Secondary
    Goat Anti-Mouse IgG (H&L)-HRP at 1/2500 dilution

    Predicted band size : 47 kDa
    Observed band size : 47 kDa

Anti-TMEM49 antibody (ab69224)参考文献

This product has been referenced in:
  • Qu A  et al. Hypoxia-inducible MiR-210 is an independent prognostic factor and contributes to metastasis in colorectal cancer. PLoS One 9:e90952 (2014). WB ; Human . Read more (PubMed: 24632577) »
  • Lo Ré AE  et al. Novel AKT1-GLI3-VMP1 Pathway Mediates KRAS Oncogene-induced Autophagy in Cancer Cells. J Biol Chem 287:25325-34 (2012). WB ; Human . Read more (PubMed: 22535956) »

See all 2 Publications for this product

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