Anti-TMEM16B抗体(ab91573)
Key features and details
- Rabbit polyclonal to TMEM16B
- Suitable for: ICC/IF, WB, IHC-P
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-TMEM16B抗体
参阅全部 TMEM16B 一抗 -
描述
兔多克隆抗体to TMEM16B -
宿主
Rabbit -
特异性
This antibody will not cross-react with TMEM16A. -
经测试应用
适用于: ICC/IF, WB, IHC-Pmore details -
种属反应性
与反应: Human -
免疫原
Synthetic peptide corresponding to Human TMEM16B (N terminal).
Database link: Q9NQ90 -
常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at +4°C. -
存储溶液
pH: 7.2
Preservative: 0.02% Sodium azide
Constituent: PBS -
Concentration information loading...
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纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Positive Controls
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab91573于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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ICC/IF |
Use a concentration of 20 µg/ml.
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WB |
Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 110 kDa.
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IHC-P |
Use a concentration of 5 µg/ml.
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说明 |
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ICC/IF
Use a concentration of 20 µg/ml. |
WB
Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 110 kDa. |
IHC-P
Use a concentration of 5 µg/ml. |
靶标
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功能
Acts as a calcium-activated chloride channel (CaCC), mostly in photoreceptors. May mediate olfactory amplification in olfactory sensory neurons (OSNs) and light perception amplification in retina. -
组织特异性
Retina, especially in the photoreceptor synaptic terminals. -
序列相似性
Belongs to the anoctamin family. -
细胞定位
Cell membrane. - Information by UniProt
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数据库链接
- Entrez Gene: 57101 Human
- Omim: 610109 Human
- SwissProt: Q9NQ90 Human
- Unigene: 148970 Human
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别名
- Ano2 antibody
- ANO2_HUMAN antibody
- Anoctamin 2 antibody
see all
图片
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Immunohistochemical analysis of human brain tissue labelling TMEM16B with ab91573 at 5 ug/mL.
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All lanes : Anti-TMEM16B antibody (ab91573) at 2 µg/ml
All lanes : Human small intestine tissue lysate
Predicted band size: 110 kDa
Observed band size: 107 kDa why is the actual band size different from the predicted? -
Immunofluorescence of TMEM16B in Human Brain cells using ab91573 at 20 ug/ml.
实验方案
数据表及文件
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SDS download
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Datasheet download
文献 (1)
ab91573 被引用在 1 文献中.
- Yamamura H et al. TMEM16A and TMEM16B channel proteins generate Ca2+-activated Cl- current and regulate melatonin secretion in rat pineal glands. J Biol Chem 293:995-1006 (2018). PubMed: 29187602