Anti-TMEM16B抗体(ab113443)

概述

  • 产品名称Anti-TMEM16B抗体
    参阅全部 TMEM16B 一抗
  • 描述
    兔多克隆抗体to TMEM16B
  • 经测试应用适用于: WB, ELISA, IHC-Pmore details
  • 种属反应性
    与反应: Rat, Human
    预测可用于: Mouse
  • 免疫原

    Synthetic peptide from the N terminal region of Human TMEM16B, conjugated to KLH.

  • 阳性对照
    • Human small intestine and spleen tissues; Rat brain tissue lysate

性能

应用

Our Abpromise guarantee covers the use of ab113443 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 114 kDa.
ELISA Use at an assay dependent concentration.
IHC-P Use a concentration of 5 µg/ml.

靶标

  • 功能Acts as a calcium-activated chloride channel (CaCC), mostly in photoreceptors. May mediate olfactory amplification in olfactory sensory neurons (OSNs) and light perception amplification in retina.
  • 组织特异性Retina, especially in the photoreceptor synaptic terminals.
  • 序列相似性Belongs to the anoctamin family.
  • 细胞定位Cell membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Ano2 antibody
    • ANO2_HUMAN antibody
    • Anoctamin 2 antibody
    • Anoctamin-2 antibody
    • C12orf3 antibody
    • Chromosome 12 open reading frame 3 antibody
    • DKFZp434P102 antibody
    • Transmembrane protein 16B (eight membrane-spanning domains) antibody
    • Transmembrane protein 16B antibody
    see all

Anti-TMEM16B antibody 图像

  • ab113443, at 5 µg/ml, staining TMEM16B in formalin fixed, paraffin embedded Human small intestine tissue by Immunohistochemistry.
  • ab113443, at 5 µg/ml, staining TMEM16B in formalin fixed, paraffin embedded Human spleen tissue by Immunohistochemistry.
  • Lane 1 : Anti-TMEM16B antibody (ab113443) at 1 µg/ml
    Lane 2 : Anti-TMEM16B antibody (ab113443) at 2 µg/ml

    Lane 1 : Rat brain tissue lysate
    Lane 2 : Rat brain tissue lysate


    Predicted band size : 114 kDa

Anti-TMEM16B antibody (ab113443)参考文献

ab113443 has not yet been referenced specifically in any publications.

Product Wall

Abcam guarantees this product to work in the species/application used in this Abreview.
Application Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Sample Human Tissue sections (Colon Ca)
Specification Colon Ca
Fixative Paraformaldehyde
Antigen retrieval step Heat mediated
Permeabilization No
Blocking step BSA as blocking agent for 30 minute(s) · Concentration: 2% · Temperature: 20°C
Username

Abcam user community

Verified customer

提交于 Oct 18 2012

Application Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Sample Pig Tissue sections (retina)
Specification retina
Fixative Paraformaldehyde
Antigen retrieval step Heat mediated
Blocking step Zytomed Blocking Reagent as blocking agent for 30 minute(s) · Concentration: 0% · Temperature: 20°C
Username

Ms. Andrea Dannullis

Verified customer

提交于 Oct 17 2012

The laboratory that produces ab113443 has sent the alignment of the immunogen with the rat and mouse proteins. As I mentioned in my previous e-mail, the identity of the immunogen sequence is considered proprietary. Homology between human and mo...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"