• 产品名称Anti-TLR7抗体
    参阅全部 TLR7 一抗
  • 描述
    兔多克隆抗体to TLR7
  • 经测试应用适用于: WB, Flow Cytmore details
  • 种属反应性
    与反应: Mouse, Human
    预测可用于: Rat
  • 免疫原

    Synthetic peptide:


    conjugated to KLH, corresponding to amino acids 706-728 of Human TLR7.

  • 阳性对照
    • Human Ramos cells, Raw cells.



Our Abpromise guarantee covers the use of ab13730 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
Flow Cyt
  • 应用说明Flow Cyt: Use at a concentration of 2 - 5 µg/1 x 106cells (Ramos or Raw cells).
    WB: Use at a concentration of 1 - 3 µg/ml for raw cell lysate. Predicted molecular weight: 121 kDa. In human Ramos cells and Raw cells, additional bands are seen (Raw cells the 121 kDa band is seen plus another lower molecular weight band).

    Not tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific of microorganisms. TLR7 is a nucleotide-sensing TLR which is activated by single-stranded RNA. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.
    • 组织特异性Detected in brain, placenta, spleen, stomach, small intestine, lung and in plasmacytoid pre-dendritic cells.
    • 序列相似性Belongs to the Toll-like receptor family.
      Contains 27 LRR (leucine-rich) repeats.
      Contains 1 TIR domain.
    • 细胞定位Endoplasmic reticulum membrane. Endosome. Lysosome. Cytoplasmic vesicle > phagosome. Relocalizes from endoplasmic reticulum to endosome and lysosome upon stimulation with agonist.
    • Information by UniProt
    • 数据库链接
    • 别名
      • PRO285 antibody
      • TLR 7 antibody
      • Tlr7 antibody
      • TLR7_HUMAN antibody
      • Toll like receptor 7 antibody
      • Toll-like receptor 7 antibody
      • UNQ248 antibody
      see all

    Anti-TLR7 antibody 图像

    • Predicted band size : 121 kDa

      Western blot analysis of TLR7 in raw cell lysate using ab13730 at 1µg/ml.

    Anti-TLR7 antibody (ab13730)参考文献

    ab13730 has not yet been referenced specifically in any publications.

    Product Wall

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