Anti-TLR6抗体[TLR6.127] (FITC) (ab72362)

概述

  • 产品名称Anti-TLR6抗体[TLR6.127] (FITC)
    参阅全部 TLR6 一抗
  • 描述
    小鼠单克隆抗体[TLR6.127] to TLR6 (FITC)
  • 偶联物FITC. Ex: 493nm, Em: 528nm
  • 经测试应用适用于: Flow Cyt, ICC/IFmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    BALB/c mice were immunized with Ba/F3 cells that stably expressed human Myc-tagged TLR6.

性能

应用

Our Abpromise guarantee covers the use of ab72362 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
Flow Cyt 1/50. ab91356-Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.
ICC/IF 1/50.

靶标

  • 功能Participates in the innate immune response to Gram-positive bacteria and fungi. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Recognizes mycoplasmal macrophage-activating lipopeptide-2kD (MALP-2), soluble tuberculosis factor (STF), phenol-soluble modulin (PSM) and B.burgdorferi outer surface protein A lipoprotein (OspA-L) cooperatively with TLR2.
  • 组织特异性Detected in monocytes, CD11c+ immature dendritic cells, plasmacytoid pre-dendritic cells and dermal microvessel endothelial cells.
  • 序列相似性Belongs to the Toll-like receptor family.
    Contains 12 LRR (leucine-rich) repeats.
    Contains 1 LRRCT domain.
    Contains 1 TIR domain.
  • 细胞定位Cell membrane. Cytoplasmic vesicle > phagosome membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • CD286 antibody
    • CD286 antigen antibody
    • TLR 6 antibody
    • Tlr6 antibody
    • TLR6_HUMAN antibody
    • Toll like receptor 6 precursor antibody
    • Toll-like receptor 6 antibody
    see all

Anti-TLR6 antibody [TLR6.127] (FITC) (ab72362)参考文献

ab72362 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"