Anti-TLR6抗体[hPer6] (ab95741)

概述

  • 产品名称Anti-TLR6抗体[hPer6]
    参阅全部 TLR6 一抗
  • 描述
    大鼠单克隆抗体[hPer6] to TLR6
  • 经测试应用适用于: Flow Cytmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant Human TLR6

  • 阳性对照
    • Human MEG-01 cell line

性能

应用

Our Abpromise guarantee covers the use of ab95741 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
Flow Cyt Use 0.25µg for 105-8 cells.
Use in a final volume of 100 µL.



ab18450-Rat monoclonal IgG2a, is suitable for use as an isotype control with this antibody.

靶标

  • 功能Participates in the innate immune response to Gram-positive bacteria and fungi. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Recognizes mycoplasmal macrophage-activating lipopeptide-2kD (MALP-2), soluble tuberculosis factor (STF), phenol-soluble modulin (PSM) and B.burgdorferi outer surface protein A lipoprotein (OspA-L) cooperatively with TLR2.
  • 组织特异性Detected in monocytes, CD11c+ immature dendritic cells, plasmacytoid pre-dendritic cells and dermal microvessel endothelial cells.
  • 序列相似性Belongs to the Toll-like receptor family.
    Contains 12 LRR (leucine-rich) repeats.
    Contains 1 LRRCT domain.
    Contains 1 TIR domain.
  • 细胞定位Cell membrane. Cytoplasmic vesicle > phagosome membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • CD286 antibody
    • CD286 antigen antibody
    • TLR 6 antibody
    • Tlr6 antibody
    • TLR6_HUMAN antibody
    • Toll like receptor 6 precursor antibody
    • Toll-like receptor 6 antibody
    see all

Anti-TLR6 antibody [hPer6] 图像

  • ab95741 at 0.25µg staining TLR5 in MEG-01 cell line cells (blue histogram) followed by Anti-Rat IgG Biotin and Streptavidin PE, compared with 0.25 µg of Rat IgG2a ? Isotype Control (open histogram).

Anti-TLR6 antibody [hPer6] (ab95741)参考文献

ab95741 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab95741.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"