• 产品名称Anti-TLR5抗体
    参阅全部 TLR5 一抗
  • 描述
    兔多克隆抗体to TLR5
  • 经测试应用适用于: WB, IHC-P, Flow Cytmore details
  • 种属反应性
    与反应: Mouse, Rat, Human
  • 免疫原

    Synthetic peptide:


    , corresponding to amino acids 300-350 of Human TLR5.

  • 阳性对照
    • Ramos and Raw cell lysate.



Our Abpromise guarantee covers the use of ab13868 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/1000. Predicted molecular weight: 103 kDa.
IHC-P Use a concentration of 10 µg/ml.
Flow Cyt Use 1-2µg for 106 cells. ab171870-Rabbit polyclonal IgG, is suitable for use as an isotype control with this antibody.


  • 功能Participates in the innate immune response to microbial agents. Mediates detection of bacterial flagellins. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.
  • 组织特异性Highly expressed in ovary and in peripheral blood leukocytes, especially in monocytes, less in CD11c+ immature dendritic cells. Also detected in prostate and testis.
  • 疾病相关Systemic lupus erythematosus 1
  • 序列相似性Belongs to the Toll-like receptor family.
    Contains 22 LRR (leucine-rich) repeats.
    Contains 1 LRRCT domain.
    Contains 1 TIR domain.
  • 翻译后修饰Phosphorylated at Ser-805 by PKD/PRKD1; phosphorylation induces the production of inflammatory cytokines.
    Phosphorylated at Tyr-798 upon flagellin binding; required for signaling.
  • 细胞定位Membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • FLJ10052 antibody
    • MGC126430 antibody
    • MGC126431 antibody
    • SLEB1 antibody
    • TIL 3 antibody
    • TIL3 antibody
    • TLR 5 antibody
    • Tlr5 antibody
    • TLR5_HUMAN antibody
    • Toll like receptor 5 antibody
    • Toll like receptor 5 precursor antibody
    • Toll-like receptor 5 antibody
    • Toll/interleukin 1 receptor like protein 3 antibody
    • Toll/interleukin-1 receptor-like protein 3 antibody
    see all

Anti-TLR5 antibody 图像

  • All lanes : Anti-TLR5 antibody (ab13868) at 2 µg/ml

    Lane 1 : Ramos whole cell lysate
    Lane 2 : Raw whole cell lysate
    Lane 3 : Mouse spleen whole cell lysate
    Lane 4 : Mouse lung whole cell lysate
    Lane 5 : Rat lung whole cell lysate

    Predicted band size : 103 kDa
    Observed band size : 97 kDa (why is the actual band size different from the predicted?)
    Additional bands at : 36 kDa. We are unsure as to the identity of these extra bands.
  • An isotype control (top) and ab13868 (bottom), at 10 µg/ml, staining TLR5 in Human Stomach tumor tissue by Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections).
  • Intracellular flow analysis of TLR5 in Balb/c mouse splenocytes using ab13868 at 2 ug/106 cells. Shaded histogram represents cells without antibody; green represents a rabbit IgG isotype control; red represents anti-TLR5 antibody. Goat anti-rabbit PE (ab47646) was used as secondary antibody.

Anti-TLR5 antibody (ab13868)参考文献

ab13868 has not yet been referenced specifically in any publications.

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