Anti-TLR2抗体[TL2.1] (FITC) (ab13553)


  • 产品名称Anti-TLR2抗体[TL2.1] (FITC)
    参阅全部 TLR2 一抗
  • 描述
    小鼠单克隆抗体[TL2.1] to TLR2 (FITC)
  • 偶联物FITC. Ex: 493nm, Em: 528nm
  • 经测试应用适用于: Flow Cyt, IP, ICCmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    CHO cells transfected with human TLR2 cDNA

  • 常规说明Avoid temparature fluctuations.



Our Abpromise guarantee covers the use of ab13553 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
Flow Cyt Use 2-5µg for 106 cells. ab91362-Mouse monoclonal IgG2a, is suitable for use as an isotype control with this antibody.
IP Use a concentration of 2 - 5 µg/ml.
ICC Use a concentration of 10 µg/ml.


  • 功能Cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components. Cooperates with TLR1 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. May also promote apoptosis in response to lipoproteins. Recognizes mycoplasmal macrophage-activating lipopeptide-2kD (MALP-2), soluble tuberculosis factor (STF), phenol-soluble modulin (PSM) and B.burgdorferi outer surface protein A lipoprotein (OspA-L) cooperatively with TLR6.
  • 组织特异性Highly expressed in peripheral blood leukocytes, in particular in monocytes, in bone marrow, lymph node and in spleen. Also detected in lung and in fetal liver. Levels are low in other tissues.
  • 序列相似性Belongs to the Toll-like receptor family.
    Contains 14 LRR (leucine-rich) repeats.
    Contains 1 TIR domain.
  • 翻译后修饰Glycosylation of Asn-442 is critical for secretion of the N-terminal ectodomain of TLR2.
  • 细胞定位Membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • CD282 antibody
    • CD282 antigen antibody
    • TIL 4 antibody
    • TIL4 antibody
    • TLR 2 antibody
    • TLR2 antibody
    • TLR2_HUMAN antibody
    • Toll like receptor 2 antibody
    • Toll like receptor 2 precursor antibody
    • Toll-like receptor 2 antibody
    • Toll/interleukin 1 receptor like 4 antibody
    • Toll/interleukin 1 receptor like protein 4 antibody
    • Toll/interleukin receptor like protein 4 antibody
    • Toll/interleukin-1 receptor-like protein 4 antibody
    see all

Anti-TLR2 antibody [TL2.1] (FITC) (ab13553)参考文献

This product has been referenced in:
  • Burgener IA & Jungi TW Antibodies specific for human or murine Toll-like receptors detect canine leukocytes by flow cytometry. Vet Immunol Immunopathol 124:184-91 (2008). Read more (PubMed: 18439687) »
  • Do JE  et al. Effects of vitamin D on expression of Toll-like receptors of monocytes from patients with Behcet's disease. Rheumatology (Oxford) 47:840-8 (2008). Read more (PubMed: 18411217) »

See all 13 Publications for this product

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ab114070 is a mouse monoclonal in which human TLR2 was expressed. That is, the antibodies from mice were raised against human TLR2 full length.

ab13553: As stated on the data sheet CHO cells transfected...

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As far as I can tell, these two antibodies are very similar and should give the same results. With regards to their specificity, ab114070 was raised against human TLR2 whereas, ab13553 was raised against human TL...

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