概述

  • 产品名称
    Anti-TLR13抗体
  • 描述
    兔多克隆抗体to TLR13
  • 经测试应用
    适用于: WBmore details
  • 种属反应性
    与反应: Mouse
    预测可用于: Rat
  • 免疫原

    Synthetic peptide conjugated to KLH derived from within residues 950 to the C-terminus of Mouse TLR13.

    (Peptide available as ab60788.)

  • 阳性对照
    • This antibody gave a positive signal in the following Mouse lysates: Brain Tissue Testis Tissue Kidney Tissue NIH 3T3 Whole Cell

性能

应用

Our Abpromise guarantee covers the use of ab60789 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Detects a band of approximately 120 kDa (predicted molecular weight: 114 kDa).

靶标

  • 相关性
    The TLRs form a family of ligand-binding proteins that engage a variety of microbial products, that on binding, activate signaling cascades leading to the synthesis of proinflammatory molecules. TLR13 is found in mouse and participates in the innate immune response to microbial agents. It acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response
  • 细胞定位
    Plasma membrane
  • 数据库链接
  • 别名
    • Toll like receptor 13 antibody

图片

  • All lanes : Anti-TLR13 antibody (ab60789) at 1 µg/ml

    Lane 1 : Brain (Mouse) Tissue Lysate
    Lane 2 : Testis (Mouse) Tissue Lysate - normal tissue
    Lane 3 : Liver (Mouse) Tissue Lysate - normal tissue
    Lane 4 : Heart (Mouse) Tissue Lysate
    Lane 5 : Kidney (Mouse) Tissue Lysate
    Lane 6 : NIH 3T3 whole cell lysate (ab7179)

    Lysates/proteins at 10 µg per lane.

    Secondary
    Goat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilution

    Performed under reducing conditions.

    Predicted band size : 114 kDa
    Observed band size : 120 kDa (why is the actual band size different from the predicted?)
    Additional bands at : 40 kDa,54 kDa. We are unsure as to the identity of these extra bands.

实验方案

文献

ab60789 has not yet been referenced specifically in any publications.

客户评价及客户问答

There are currently no Customer reviews or Questions for ab60789.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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