概述

  • 产品名称Anti-TLR13抗体
  • 描述
    兔多克隆抗体to TLR13
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Mouse
    预测可用于: Rat
  • 免疫原

    Synthetic peptide conjugated to KLH derived from within residues 950 to the C-terminus of Mouse TLR13.

    (Peptide available as ab60788.)

  • 阳性对照
    • This antibody gave a positive signal in the following Mouse lysates: Brain Tissue Testis Tissue Kidney Tissue NIH 3T3 Whole Cell

性能

应用

Our Abpromise guarantee covers the use of ab60789 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Detects a band of approximately 120 kDa (predicted molecular weight: 114 kDa).

靶标

  • 相关性The TLRs form a family of ligand-binding proteins that engage a variety of microbial products, that on binding, activate signaling cascades leading to the synthesis of proinflammatory molecules. TLR13 is found in mouse and participates in the innate immune response to microbial agents. It acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response
  • 细胞定位Plasma membrane
  • 数据库链接
  • 别名
    • Toll like receptor 13 antibody

Anti-TLR13 antibody 图像

  • All lanes : Anti-TLR13 antibody (ab60789) at 1 µg/ml

    Lane 1 : Brain (Mouse) Tissue Lysate
    Lane 2 : Testis (Mouse) Tissue Lysate - normal tissue
    Lane 3 : Liver (Mouse) Tissue Lysate - normal tissue
    Lane 4 : Heart (Mouse) Tissue Lysate
    Lane 5 : Kidney (Mouse) Tissue Lysate
    Lane 6 : NIH 3T3 whole cell lysate (ab7179)

    Lysates/proteins at 10 µg per lane.

    Secondary
    Goat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilution

    Performed under reducing conditions.

    Predicted band size : 114 kDa
    Observed band size : 120 kDa (why is the actual band size different from the predicted?)
    Additional bands at : 40 kDa,54 kDa. We are unsure as to the identity of these extra bands.

Anti-TLR13 antibody (ab60789)参考文献

ab60789 has not yet been referenced specifically in any publications.

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