概述

  • 产品名称Anti-TLR11抗体
    参阅全部 TLR11 一抗
  • 描述
    兔多克隆抗体to TLR11
  • 特异性ab24183 reacts with toll-like receptor 11(TLR11)
  • 经测试应用适用于: ICC/IF, WBmore details
  • 种属反应性
    与反应: Mouse
  • 免疫原

    Synthetic peptide (Mouse) corresponding to 16 amino acids between the middle and carboxy terminus of mouse TLR11(GenBank accession no. NP_991388).

  • 阳性对照
    • RAW264.7 cell lysates.

性能

相关产品

应用

Our Abpromise guarantee covers the use of ab24183 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ICC/IF Use a concentration of 10 µg/ml.
WB Use a concentration of 0.5 - 2 µg/ml. Detects a band of approximately 95 kDa (predicted molecular weight: 105 kDa).Can be blocked with Active mouse TLR11 peptide (ab39868).

靶标

  • 相关性Toll like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. These proteins act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors. TLR11 is one of three mouse TLRs that lack a human ortholog. It is activated specifically by uropathogenic bacteria, and mice lacking TLR11 showed a much greater susceptability to uropathogenic infections, indicating a potentially important role for TLR11 in preventing infections in the urogenital system.
  • 细胞定位Type I membrane protein
  • 数据库链接
  • 别名
    • hgnc31753 antibody
    • Toll like receptor 11 antibody

Anti-TLR11 antibody 图像

  • Lane 1 : Anti-TLR11 antibody (ab24183) at 0.5 µg/ml
    Lane 2 : Anti-TLR11 antibody (ab24183) at 1 µg/ml
    Lane 3 : Anti-TLR11 antibody (ab24183) at 2 µg/ml

    Lane 1 : RAW 264.7 cell lysate.
    Lane 2 : RAW 264.7 cell lysate.
    Lane 3 : RAW 264.7 cell lysate.


    Predicted band size : 105 kDa
    Observed band size : 95 kDa (why is the actual band size different from the predicted?)
  • ab24183 at 10µg/ml staining of TLR11 in RAW264.7 cells by ICC/IF

Anti-TLR11 antibody (ab24183)参考文献

ab24183 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab24183.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"