产品名称 Anti-TLR11抗体 参阅全部 TLR11 一抗
特异性 ab24183 reacts with toll-like receptor 11(TLR11)
ICC/IF, WB more details
Synthetic peptide (Mouse) corresponding to 16 amino acids between the middle and carboxy terminus of mouse TLR11(GenBank accession no. NP_991388).
存放说明 Shipped at 4°C. Store at +4°C.
存储溶液 Preservative: 0.02% Sodium Azide
Concentration information loading...
纯度 IgG fraction
纯化说明 Purified by ion exchange chromatography
Immunizing Peptide (Blocking)
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use a concentration of 10 µg/ml.
Use a concentration of 0.5 - 2 µg/ml. Detects a band of approximately 95 kDa (predicted molecular weight: 105 kDa).Can be blocked with
Active mouse TLR11 peptide (ab39868).
相关性 Toll like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. These proteins act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors. TLR11 is one of three mouse TLRs that lack a human ortholog. It is activated specifically by uropathogenic bacteria, and mice lacking TLR11 showed a much greater susceptability to uropathogenic infections, indicating a potentially important role for TLR11 in preventing infections in the urogenital system.
细胞定位 Type I membrane protein
Toll like receptor 11 antibody
Anti-TLR11 antibody 图像
Western blot - Anti-TLR11 antibody (ab24183)
Lane 1 : Anti-TLR11 antibody (ab24183) at 0.5 µg/ml Lane 2 : Anti-TLR11 antibody (ab24183) at 1 µg/ml Lane 3 : Anti-TLR11 antibody (ab24183) at 2 µg/ml Lane 1 : RAW 264.7 cell lysate. Lane 2 : RAW 264.7 cell lysate. Lane 3 : RAW 264.7 cell lysate. Predicted band size : 105 kDa Observed band size : 95 kDa ( why is the actual band size different from the predicted?)
Immunocytochemistry/ Immunofluorescence - TLR11 antibody (ab24183)
ab24183 at 10µg/ml staining of TLR11 in RAW264.7 cells by ICC/IF
Anti-TLR11 antibody (ab24183)参考文献
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"