FITC荧光Anti-TIL/TLR1抗体[GD2.F4] (ab59702)
Key features and details
- FITC Mouse monoclonal [GD2.F4] to TIL/TLR1
- Suitable for: Flow Cyt
- Reacts with: Human
- Conjugation: FITC. Ex: 493nm, Em: 528nm
- Isotype: IgG1
概述
-
产品名称
FITC荧光Anti-TIL/TLR1抗体[GD2.F4]
参阅全部 TIL/TLR1 一抗 -
描述
FITC荧光小鼠单克隆抗体[GD2.F4] to TIL/TLR1 -
宿主
Mouse -
偶联物
FITC. Ex: 493nm, Em: 528nm -
特异性
This antibody reacts with human TIL/TLR1. It does not recognize TLR2, TLR4 or TLR4 in association with MD2. -
经测试应用
适用于: Flow Cytmore details -
种属反应性
与反应: Human -
免疫原
Tissue, cells or virus corresponding to Human TIL/TLR1. HeLa cells transfected with TLR1 mRNA
-
常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
-
形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C. -
存储溶液
Preservative: 0.02% Sodium azide
Constituents: PBS, 1% BSA -
Concentration information loading...
-
纯度
Protein G purified -
纯化说明
0.2µm filtered solution. -
克隆
单克隆 -
克隆编号
GD2.F4 -
同种型
IgG1 -
研究领域
相关产品
-
Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab59702于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
---|---|---|
Flow Cyt | (1) |
Use 10µl for 106 cells.
ab91356 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody. |
说明 |
---|
Flow Cyt
Use 10µl for 106 cells. ab91356 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody. |
靶标
-
功能
Participates in the innate immune response to microbial agents. Cooperates with TLR2 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. -
组织特异性
Ubiquitous. Highly expressed in spleen, ovary, peripheral blood leukocytes, thymus and small intestine. -
序列相似性
Belongs to the Toll-like receptor family.
Contains 12 LRR (leucine-rich) repeats.
Contains 1 LRRCT domain.
Contains 1 TIR domain. -
细胞定位
Cell membrane. Cytoplasmic vesicle > phagosome membrane. - Information by UniProt
-
数据库链接
- Entrez Gene: 7096 Human
- Omim: 601194 Human
- SwissProt: Q15399 Human
- Unigene: 621817 Human
- Unigene: 654532 Human
-
别名
- CD281 antibody
- CD281 antigen antibody
- KIAA0012 antibody
see all
图片
-
Overlay histogram showing TIL/THP1 cells stained with ab59702 (red line). The cells were fixed with 80% methanol (5 min) and incubated in 1x PBS / 10% normal goat serum / 0.3M glycine to block non-specific protein-protein interactions. The cells were then incubated with the antibody (ab59702, 1µg/1x106 cells) for 30 min at 22ºC. Isotype control antibody (black line) was mouse IgG1 FITC (1µg/1x106 cells) used under the same conditions. Acquisition of >5,000 events was performed.
Please note that Abcam do not have any data for use of this antibody on non-fixed cells. We welcome any customer feedback.
数据表及文件
-
Datasheet download
文献 (0)
ab59702 尚未被引用在任何文献中。