RabMAb

Anti-TLR1抗体[EPR2075] (ab68158)

概述

  • 产品名称Anti-TLR1抗体[EPR2075]
    参阅全部 TLR1 一抗
  • 描述
    兔单克隆抗体[EPR2075] to TLR1
  • 经测试应用适用于: WB, IP, Flow Cytmore details
    不适用于: ICC or IHC-P
  • 种属反应性
    与反应: Human
  • 免疫原

    A synthetic peptide corresponding to residues on the extracellular region of human TLR1

  • 阳性对照
    • WB: Daudi and Ramos cell lysates. Flow Cyt: Daudi cells.
  • 常规说明

    This product is a recombinant rabbit monoclonal antibody.

    Produced using Abcam’s RabMAb® technology. RabMAb® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.

    Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

性能

应用

Our Abpromise guarantee covers the use of ab68158 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
IP
Flow Cyt
  • 应用说明Flow Cyt: 1/60.
    IP: 1/40.
    WB: 1/1000 - 1/2000. Detects a band of approximately 90 and 125 kDa (predicted molecular weight: 90 kDa).

    Is unsuitable for ICC or IHC-P.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Participates in the innate immune response to microbial agents. Cooperates with TLR2 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.
    • 组织特异性Ubiquitous. Highly expressed in spleen, ovary, peripheral blood leukocytes, thymus and small intestine.
    • 序列相似性Belongs to the Toll-like receptor family.
      Contains 12 LRR (leucine-rich) repeats.
      Contains 1 LRRCT domain.
      Contains 1 TIR domain.
    • 细胞定位Cell membrane. Cytoplasmic vesicle > phagosome membrane.
    • Information by UniProt
    • 数据库链接
    • 别名
      • CD281 antibody
      • CD281 antigen antibody
      • KIAA0012 antibody
      • LPRS5 antibody
      • rsc786 antibody
      • TIL antibody
      • TIL. LPRS5 antibody
      • Tlr1 antibody
      • TLR1_HUMAN antibody
      • Toll (Drosophila) homolog antibody
      • Toll like receptor 1 antibody
      • Toll-like receptor 1 antibody
      • Toll/interleukin-1 receptor-like protein antibody
      see all

    Anti-TLR1 antibody [EPR2075] 图像

    • All lanes : Anti-TLR1 antibody [EPR2075] (ab68158) at 1/1000 dilution

      Lane 1 : Daudi cell lysate
      Lane 2 : Ramos cell lysate

      Lysates/proteins at 10 µg per lane.

      Secondary
      HRP labelled goat anti-rabbit at 1/2000 dilution

      Predicted band size : 90 kDa
      Observed band size : 90 kDa
      Additional bands at : 125 kDa. We are unsure as to the identity of these extra bands.
    • Flow cytometric analysis of TLR1 in Daudi cells using ab68158 at 1/60 dilution (pink) or a rabbit IgG (green).

    Anti-TLR1 antibody [EPR2075] (ab68158)参考文献

    ab68158 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"