概述
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产品名称Anti-TLR1抗体
参阅全部 TLR1 一抗 -
描述山羊多克隆抗体to TLR1
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经测试应用适用于: WB, ELISAmore details
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种属反应性与反应: Human
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免疫原
Recombinant full length TLR1 protein (Human).
性能
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形式Liquid
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存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
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存储溶液Preservative: 0.02% Sodium Azide.
Constituents: 50% Glycerol, 1% BSA, PBS. -
Concentration information loading... -
纯度Immunogen affinity purified
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克隆多克隆
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同种型IgG
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研究领域
相关产品
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Compatible Secondaries
应用
Our Abpromise guarantee covers the use of ab19006 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB | Use a concentration of 0.5 - 1 µg/ml. Predicted molecular weight: 90 kDa. | |
| ELISA | Use a concentration of 1 - 4 µg/ml. |
靶标
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功能Participates in the innate immune response to microbial agents. Cooperates with TLR2 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.
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组织特异性Ubiquitous. Highly expressed in spleen, ovary, peripheral blood leukocytes, thymus and small intestine.
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序列相似性Belongs to the Toll-like receptor family.
Contains 12 LRR (leucine-rich) repeats.
Contains 1 LRRCT domain.
Contains 1 TIR domain. -
细胞定位Cell membrane. Cytoplasmic vesicle > phagosome membrane.
- Information by UniProt
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数据库链接
- Entrez Gene: 7096 Human
- Omim: 601194 Human
- SwissProt: Q15399 Human
- Unigene: 621817 Human
- Unigene: 654532 Human
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别名
- CD281 antibody
- CD281 antigen antibody
- KIAA0012 antibody
see all
Anti-TLR1 antibody (ab19006)参考文献
ab19006 has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"