1/50 - 1/100. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
功能Protease which processes procollagen C-propeptides, such as chordin, pro-biglycan and pro-lysyl oxidase. Required for the embryonic development. Predominant protease, which in the development, influences dorsal-ventral patterning and skeletogenesis.
疾病相关Defects in TLL1 are the cause of atrial septal defect type 6 (ASD6) [MIM:613087]. A congenital heart malformation characterized by incomplete closure of the wall between the atria resulting in blood flow from the left to the right atria.
序列相似性Belongs to the peptidase M12A family. Contains 5 CUB domains. Contains 2 EGF-like domains.
Immunohistochemistry analysis in formalin fixed and paraffin embedded Human prostate carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. ab107743 at a dilution of 1/50.
Anti-TLL1 antibody (ab107743)参考文献
has not yet been referenced specifically in any publications.