概述

  • 产品名称Anti-TLE3抗体
    参阅全部 TLE3 一抗
  • 描述
    兔多克隆抗体to TLE3
  • 经测试应用适用于: ELISA, WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Dog, Pig
  • 免疫原

    Synthetic peptide: KDEKNHHELD HRERESSANN SVSPSESLRA SEKHRGSADY SMEAKKRKAE, corresponding to a region within N terminal amino acids 181-230 of Human TLE3.

  • 阳性对照
    • HepG2 cell lysate.

性能

相关产品

应用

Our Abpromise guarantee covers the use of ab32992 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA 1/62500.
WB Use a concentration of 2.5 µg/ml. Predicted molecular weight: 83 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能Transcriptional corepressor that binds to a number of transcription factors. Inhibits the transcriptional activation mediated by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES.
  • 组织特异性Placenta and lung.
  • 序列相似性Belongs to the WD repeat Groucho/TLE family.
    Contains 7 WD repeats.
  • 翻译后修饰Ubiquitinated by XIAP/BIRC4. This ubiquitination does not affect its stability, nuclear localization, or capacity to tetramerize but inhibits its interaction with TCF7L2/TCF4.
  • 细胞定位Nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • E(sp1) homolog Drosophila antibody
    • Enhancer of split groucho 3 antibody
    • Enhancer of split groucho-like protein 3 antibody
    • ESG 3 antibody
    • ESG antibody
    • ESG3 antibody
    • FLJ39460 antibody
    • GRG 3 antibody
    • GRG3 antibody
    • HsT18976 antibody
    • KIAA1547 antibody
    • TLE 3 antibody
    • Tle3 antibody
    • TLE3_HUMAN antibody
    • Transducin like enhancer of split 3 antibody
    • Transducin like enhancer of split 3 homolog of Drosophila E(sp1) antibody
    • Transducin like enhancer protein 3 antibody
    • transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila) antibody
    • Transducin-like enhancer protein 3 antibody
    see all

Anti-TLE3 antibody 图像

Anti-TLE3 antibody (ab32992)参考文献

ab32992 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab32992.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"