概述

  • 产品名称Anti-TIPRL抗体
    参阅全部 TIPRL 一抗
  • 描述
    兔多克隆抗体to TIPRL
  • 经测试应用适用于: WBmore details
    不适用于: IP
  • 种属反应性
    与反应: Mouse, Human
    预测可用于: Rat, Rabbit, Chimpanzee, Rhesus monkey, Gorilla, Orangutan
  • 免疫原

    Synthetic peptide corresponding to a region between residues 200 and 250 of human TIPRL (NP_690866.1)

  • 阳性对照
    • HeLa, 293T and NIH3T3 whole cell lysates.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液Preservative: 0.09% Sodium Azide
    Constituents: 0.1% BSA, Tris buffered saline
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 纯化说明ab71974 was affinity purified using an epitope specific to TIPRL immobilized on solid support.
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab71974 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/2000 - 1/10000. Detects a band of approximately 29 kDa (predicted molecular weight: 32 kDa).
  • 应用说明Is unsuitable for IP.
  • 靶标

    • 功能May be a allosteric regulator of serine/threonine-protein phosphatase 2A (PP2A). Isoform 1 inhibits catalytic activity of the PP2A(D) core complex in vitro. The PP2A(C):TIPRL complex does not show phosphatase activity. May play a role in the regulation of ATM/ATR signaling pathway controlling DNA replication and repair.
    • 序列相似性Belongs to the TIP41 family.
    • 翻译后修饰Phosphorylated upon DNA damage, probably by ATM or ATR.
    • 细胞定位Cytoplasm.
    • Information by UniProt
    • 数据库链接
    • 别名
      • 1810011K17Rik antibody
      • dJ69E11.3 antibody
      • MGC3794 antibody
      • Putative MAPK activating protein PM10 antibody
      • Putative MAPK-activating protein PM10 antibody
      • RP1-69E11.1 antibody
      • Tip antibody
      • TIP41 antibody
      • TIP41-like protein antibody
      • tiprl antibody
      • TIPRL_HUMAN antibody
      • TOR Signaling Pathway Regulator like antibody
      • Type 2A-interacting protein antibody
      see all

    Anti-TIPRL antibody 图像

    • All lanes : Anti-TIPRL antibody (ab71974) at 0.04 µg/ml

      Lane 1 : HeLa whole cell lysate at 50 µg
      Lane 2 : HeLa whole cell lysate at 15 µg
      Lane 3 : HeLa whole cell lysate at 5 µg
      Lane 4 : 293T whole cell lysate at 50 µg
      Lane 5 : NIH3T3 whole cell lysate at 50 µg


      Predicted band size : 32 kDa
      Observed band size : 29 kDa (why is the actual band size different from the predicted?)


      Exposure time : 30 seconds

    Anti-TIPRL antibody (ab71974)参考文献

    ab71974 has not yet been referenced specifically in any publications.

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