概述

  • 产品名称
  • 描述
    山羊多克隆抗体to TIPRL
  • 特异性
    ab104251 is expected to recognize isoform 1 (NP_690866.1).
  • 经测试应用
    适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Dog
  • 免疫原

    Synthetic peptide:

    C-RIDPNPADSQKSTQ

    , corresponding to C terminal amino acids 257-270 of Human TIPRL (NP_690866.1).

  • 阳性对照
    • K562 lysate.

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液
    Preservative: 0.02% Sodium Azide
    Constituents: 0.5% BSA, Tris buffered saline, pH 7.3
  • Concentration information loading...
  • 纯度
    Immunogen affinity purified
  • 纯化说明
    ab104251 was purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
  • 克隆
    多克隆
  • 同种型
    IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab104251 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 - 3 µg/ml. Predicted molecular weight: 32 kDa.

靶标

  • 功能
    May be a allosteric regulator of serine/threonine-protein phosphatase 2A (PP2A). Isoform 1 inhibits catalytic activity of the PP2A(D) core complex in vitro. The PP2A(C):TIPRL complex does not show phosphatase activity. May play a role in the regulation of ATM/ATR signaling pathway controlling DNA replication and repair.
  • 序列相似性
    Belongs to the TIP41 family.
  • 翻译后修饰
    Phosphorylated upon DNA damage, probably by ATM or ATR.
  • 细胞定位
    Cytoplasm.
  • Information by UniProt
  • 数据库链接
  • 别名
    • 1810011K17Rik antibody
    • dJ69E11.3 antibody
    • MGC3794 antibody
    • Putative MAPK activating protein PM10 antibody
    • Putative MAPK-activating protein PM10 antibody
    • RP1-69E11.1 antibody
    • Tip antibody
    • TIP41 antibody
    • TIP41-like protein antibody
    • tiprl antibody
    • TIPRL_HUMAN antibody
    • TOR signaling pathway regulator antibody
    • TOR Signaling Pathway Regulator like antibody
    • Type 2A-interacting protein antibody
    see all

图片

  • Anti-TIPRL antibody (ab104251) at 1 µg/ml + K562 lysate at 35 µg

    Predicted band size : 32 kDa

实验方案

文献

ab104251 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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