概述

  • 产品名称Anti-TIP30抗体
    参阅全部 TIP30 一抗
  • 描述
    兔多克隆抗体to TIP30
  • 经测试应用适用于: WB, ICC/IFmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant fragment containing a sequence corresponding to a region within amino acids 1-192 of Human TIP30. (Uniprot: Q9BUP3)

  • 阳性对照
    • A431 cell lysate and HeLa cell lysate.

性能

应用

Our Abpromise guarantee covers the use of ab125726 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/1000 - 1/10000. Predicted molecular weight: 27 kDa.
ICC/IF 1/100 - 1/1000.

靶标

  • 功能Oxidoreductase required for tumor suppression. NAPDH-bound form inhibits nuclear import by competing with nuclear import substrates for binding to a subset of nuclear transport receptors. May act as a redox sensor linked to transcription through regulation of nuclear import. Isoform 1 is a metastasis suppressor with proapoptotic as well as antiangiogenic properties. Isoform 2 has an antiapoptotic effect.
  • 组织特异性Ubiquitous. Highest level in liver. High levels in lung, skeletal muscle, pancreas and placenta. Moderate levels in heart and kidney. Low levels in brain. Not expressed or low levels in variant small cell lung carcinomas, 33% of hepatocellular carcinomas and neuroblastomas.
  • 结构域Unique C-terminus confers high proteasome-dependent instability to isoform 2.
  • 细胞定位Cytoplasm. Nucleus envelope.
  • Information by UniProt
  • 数据库链接
  • 别名
    • 30 kDa HIV 1 TAT interacting protein antibody
    • 30 kDa HIV-1 TAT-interacting protein antibody
    • 30 kDa HIV1 TAT interacting protein antibody
    • CC3 antibody
    • FLJ26963 antibody
    • HIV 1 Tat interacting protein 2 30kDa antibody
    • HIV 1 Tat interacting protein 2 antibody
    • HIV-1 TAT-interactive protein 2 antibody
    • HTAI2_HUMAN antibody
    • HTATIP 2 antibody
    • HTATIP2 antibody
    • Oxidoreductase HTATIP2 antibody
    • SDR44U1 antibody
    • Short chain dehydrogenase/reductase family 44U member 1 antibody
    • Tat interacting protein (30kDa) antibody
    see all

Anti-TIP30 antibody 图像

  • ab125726, at 1/500 dilution, staining TIP30 (Green) in Paraformaldehyde-fixed HeLa cells by Immunocytochemistry/Immunofluorescence.
  • All lanes : Anti-TIP30 antibody (ab125726) at 1/5000 dilution

    Lane 1 : A431 lysate at 30 µg
    Lane 2 : HeLa lysate at 30 µg


    Predicted band size : 27 kDa

Anti-TIP30 antibody (ab125726)参考文献

ab125726 has not yet been referenced specifically in any publications.

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