概述

  • 产品名称Anti-TINAG抗体
    参阅全部 TINAG 一抗
  • 描述
    兔多克隆抗体to TINAG
  • 特异性ab105512 only recognises TINAG isoform 1 (TIN1), not isoform 2 (TIN2)
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Rabbit, Horse, Guinea pig, Cow, Cat, Dog
  • 免疫原

    Synthetic peptide corresponding to a region within internal sequence amino acids 251-300 (VAADRIAIQS KGRYTANLSP QNLISCCAKN RHGCNSGSID RAWWYLRKRG) of Human TINAG (NP_055279).

  • 阳性对照
    • PANC1 cell lysate

性能

应用

Our Abpromise guarantee covers the use of ab105512 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 55 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能Mediates adhesion of proximal tubule epithelial cells via integrins alpha3-beta1 and alphaV-beta3. This is a non catalytic peptidase C1 family protein.
  • 组织特异性Expressed in the kidney cortex, small intestine and cornea.
  • 序列相似性Belongs to the peptidase C1 family.
    Contains 1 SMB (somatomedin-B) domain.
  • 发展阶段Initially observed in the Bowman capsule during early glomerular capillary loop formation in the kidney. In more developmentally mature glomeruli, following transition from early to mid-capillary loop stage, expression is higher in the proximal tubular basement membrane than in the distal basement membrane and Bowman capsule.
  • 翻译后修饰It has been suggested that the active SMB domain may be permitted considerable disulfide bond heterogeneity or variability, thus 2 alternate disulfide patterns based on 3D structures are described with 1 disulfide bond conserved in both.
  • 细胞定位Secreted > extracellular space > extracellular matrix > basement membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • TIN AG antibody
    • TIN-Ag antibody
    • TIN1 antibody
    • TIN2 antibody
    • TINAG antibody
    • TINAG_HUMAN antibody
    • Tubulointerstitial nephritis antigen antibody
    see all

Anti-TINAG antibody 图像

  • Anti-TINAG antibody (ab105512) at 1 µg/ml + PANC1 cell lysate at 10 µg

    Predicted band size : 55 kDa

Anti-TINAG antibody (ab105512)参考文献

ab105512 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab105512.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"