Store at -20°C. Stable for 12 months at -20°C
Preservative: 0.02% Sodium Azide
Constituents: 50% Glycerol, PBS (without Mg2+ and Ca2+), 150mM Sodium chloride, pH 7.4
Concentration information loading...
Immunogen affinity purified
ab58425 was affinity purified from rabbit antiserum by affinity chromatography using epitope specific immunogen.
Our Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
||Use at an assay dependent concentration. PubMed: 23525608
||Use at an assay dependent concentration.
||1/500 - 1/1000. Detects a band of approximately 26 kDa (predicted molecular weight: 26 kDa).
Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. Known to act on MMP-1, MMP-2, MMP-3, MMP-7 and MMP-9.
Abundant in heart and present at low levels in many other tissues.
Belongs to the protease inhibitor I35 (TIMP) family.
Contains 1 NTR domain.
Information by UniProt
- Metalloproteinase inhibitor 4 antibody
- TIMP 4 antibody
- TIMP metallopeptidase inhibitor 4 antibody
Anti-TIMP4 antibody 图像
Western blot - TIMP4 antibody (ab58425)
All lanes : Anti-TIMP4 antibody (ab58425) at 1/500 dilution
Lane 1 : NIH3T3 cell extract
Lane 2 : NIH3T3 cell extract with immunising peptide
Predicted band size : 26 kDa
Observed band size : 26 kDa
Immunohistochemistry (Paraffin-embedded sections) - TIMP4 antibody (ab58425)
ab58425, at 1/50 dilution, staining TIMP4 in paraffin embedded human lung carcinoma tissue by Immunohistochemistry, in the absence (left image) or presence (right image) of the immunising peptide.
Anti-TIMP4 antibody (ab58425)参考文献
This product has been referenced in:
- Sun J et al. Effect of simvastatin on MMPs and TIMPs in cigarette smoke-induced rat COPD model. Int J Chron Obstruct Pulmon Dis 12:717-724 (2017).
Read more (PubMed: 28260878) »
- Narayanan N et al. Hyperhomocysteinemia during aortic aneurysm, a plausible role of epigenetics. Int J Physiol Pathophysiol Pharmacol 5:32-42 (2013).
Read more (PubMed: 23525608) »
See all 5 Publications
for this product
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"