概述

  • 产品名称Anti-TIMP2抗体
    参阅全部 TIMP2 一抗
  • 描述
    兔多克隆抗体to TIMP2
  • 经测试应用适用于: IHC-P, WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    A synthetic peptide derived from the N terminal half of human TIMP2.

  • 阳性对照
    • Paraffin embedded Human colon carcinoma tissue.

性能

应用

Our Abpromise guarantee covers the use of ab74216 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P
WB
  • 应用说明IHC-P: 1/50 for 10 min at RT.
    Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0 for 10 min followed by cooling at RT for 20 min.
    WB: Use at an assay dependent dilution. Predicted molecular weight: 24 kDa.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-10, MMP-13, MMP-14, MMP-15, MMP-16 and MMP-19.
    • 序列相似性Belongs to the protease inhibitor I35 (TIMP) family.
      Contains 1 NTR domain.
    • 翻译后修饰The activity of TIMP2 is dependent on the presence of disulfide bonds.
    • 细胞定位Secreted.
    • Information by UniProt
    • 数据库链接
    • 别名
      • CSC 21K antibody
      • CSC-21K antibody
      • CSC21K antibody
      • Metalloproteinase inhibitor 2 antibody
      • Metalloproteinase inhibitor 2 precursor antibody
      • TIMP 2 antibody
      • TIMP metallopeptidase inhibitor 2 antibody
      • TIMP-2 antibody
      • TIMP2 antibody
      • TIMP2_HUMAN antibody
      • Tissue Inhibitor of Metalloproteinase 2 antibody
      • Tissue inhibitor of metalloproteinases 2 antibody
      see all

    Anti-TIMP2 antibody 图像

    • ab74216 at 1/50 dilution staining TIMP2 in human colon carcinoma by Immunohistochemistry, Formalin-fixed, Paraffin-embedded tissue.

    Anti-TIMP2 antibody (ab74216)参考文献

    ab74216 has not yet been referenced specifically in any publications.

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