概述

  • 产品名称Anti-TIMM9抗体
  • 描述
    小鼠单克隆抗体to TIMM9
  • 经测试应用适用于: WB, IHC-Pmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant full length protein: MAAQIPESDQ IKQFKEFLGT YNKLTETCFL DCVKDFTTRE VKPEETTCSE HCLQKYLKMT QRISMRFQEY HIQQNEALAA KAGLLGQPR, corresponding to amino acids 1-90 of Human TIMM9

性能

应用

Our Abpromise guarantee covers the use of ab57089 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
IHC-P
  • 应用说明WB: Use at a concentration of 1-5 µg/ml.
    IHC-P: Use at a concentration of 3 µg/ml.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. May also be required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.
    • 组织特异性Ubiquitous, with highest expression in heart, kidney, liver and skeletal muscle.
    • 序列相似性Belongs to the small Tim family.
    • 结构域The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space. However, during the transit of TIMM9 from cytoplasm into mitochondrion, the Cys residues probably coordinate zinc, thereby preventing folding and allowing its transfer across mitochondrial outer membrane.
    • 细胞定位Mitochondrion inner membrane.
    • Information by UniProt
    • 数据库链接
    • 别名
      • Mitochondrial import inner membrane translocase subunit Tim9 antibody
      • TIM9 antibody
      • TIM9_HUMAN antibody
      • TIM9A antibody
      • Timm9 antibody
      • TIMM9A antibody
      see all

    Anti-TIMM9 antibody 图像

    • TIMM9 antibody (ab57089) used in immunohistochemistry at 3ug/ml on formalin fixed and paraffin embedded human small Intestine.


    • Predicted band size : 10 kDa
      TIMM9 antibody (ab57089) at 1ug/lane + IMR-32 cell lysate at 25ug/lane.

    Anti-TIMM9 antibody (ab57089)参考文献

    This product has been referenced in:
    • Kang Y  et al. Tim29 is a novel subunit of the human TIM22 translocase and is involved in complex assembly and stability. Elife 5:N/A (2016). Read more (PubMed: 27554484) »

    See 1 Publication for this product

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