Anti-TIMM13抗体(ab66142)

概述

  • 产品名称Anti-TIMM13抗体
    参阅全部 TIMM13 一抗
  • 描述
    小鼠多克隆抗体to TIMM13
  • 经测试应用适用于: WB, ELISAmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant full length protein (Human) with tag

  • 阳性对照
    • Recombinant tagged TIMM13.

性能

应用

Our Abpromise guarantee covers the use of ab66142 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
ELISA
  • 应用说明ELISA: Use at an assay dependent dilution.
    WB: 1/1000 - 1/2500. Predicted molecular weight: 10 kDa.

    This antibody has only been tested in WB against the recombinant protein used as immunogen. We have no data on the detection of endogenous protein

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space. The TIMM8-TIMM13 complex mediates the import of proteins such as TIMM23, SLC25A12/ARALAR1 and SLC25A13/ARALAR2, while the predominant TIMM9-TIMM10 70 kDa complex mediates the import of much more proteins.
    • 组织特异性Ubiquitous, with highest expression in heart, kidney, liver and skeletal muscle.
    • 序列相似性Belongs to the small Tim family.
    • 结构域The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space. However, during the transit of TIMM13 from cytoplasm into mitochondrion, the Cys residues probably coordinate zinc, thereby preventing folding and allowing its transfer across mitochondrial outer membrane.
    • 细胞定位Mitochondrion inner membrane.
    • Information by UniProt
    • 数据库链接
    • 别名
      • Mitochondrial import inner membrane translocase subunit TIM13 antibody
      • Mitochondrial import inner membrane translocase subunit Tim13B antibody
      • ppv1 antibody
      • TIM 13 antibody
      • TIM13 antibody
      • TIM13_HUMAN antibody
      • TIM13B antibody
      • TIMM 13 antibody
      • Timm13 antibody
      • TIMM13A antibody
      • TIMM13B antibody
      • Translocase of inner mitochondrial membrane 13 homolog antibody
      see all

    Anti-TIMM13 antibody 图像



    • Predicted band size : 10 kDa

    Anti-TIMM13 antibody (ab66142)参考文献

    ab66142 has not yet been referenced specifically in any publications.

    Product Wall

    Application Immunoprecipitation
    Sample Human Cell lysate - other (HEK293)
    Total protein in input 300 µg
    Immuno-precipitation step Other - Protein G dynabeads
    Specification HEK293
    Username

    Dr. Edyta Marcon

    Verified customer

    提交于 Jun 26 2015

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"