概述

  • 产品名称Anti-Timeless抗体
    参阅全部 Timeless 一抗
  • 描述
    兔多克隆抗体to Timeless
  • 特异性ab51519 recognises the C terminal region of Timeless containing a SANT domain.
  • 经测试应用适用于: WB, ELISAmore details
  • 种属反应性
    与反应: Mouse, Rat
  • 免疫原

    Synthetic peptide corresponding to Mouse Timeless aa 1178-1197 (C terminal).
    Sequence:

    SGTPRVHRKKRFQIEDEDD

性能

应用

Our Abpromise guarantee covers the use of ab51519 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500. Detects a band of approximately 139 kDa (predicted molecular weight: 139 kDa).
ELISA Use at an assay dependent dilution.

靶标

  • 功能Required for normal progression of S-phase. Involved in the circadian rhythm autoregulatory loop. Negatively regulates CLOCK-NPAS2/BMAL1-induced transactivation of PER1 possibly via translocation of PER1 into the nucleus. Promotes TIPIN nuclear localiZation. Involved in cell survival after DNA damage or replication stress. May be specifically required for the ATR-CHK1 pathway in the replication checkpoint induced by hydroxyurea or ultraviolet light. May also play an important role in epithelial cell morphogenesis and formation of branching tubules.
  • 组织特异性Expressed in all tissues examined including brain, heart, lung, liver, skeletal muscle, kidney, placenta, pancreas, spleen, thymus and testis. Highest levels of expression in placenta, pancreas, thymus and testis.
  • 序列相似性Belongs to the timeless family.
  • 细胞定位Nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • FLJ12640 antibody
    • FLJ20714 antibody
    • hTIM antibody
    • Protein timeless homolog antibody
    • TIM antibody
    • TIM_HUMAN antibody
    • TIM1 antibody
    • Timeless antibody
    • timeless circadian clock 1 antibody
    • timeless circadian clock antibody
    • timeless homolog antibody
    • TIMELESS1 antibody
    • Tof1 homolog antibody
    see all

Anti-Timeless antibody 图像

  • Anti-Timeless antibody (ab51519) at 1/500 dilution

    Predicted band size : 139 kDa
    Observed band size : 139 kDa

Anti-Timeless antibody (ab51519)参考文献

ab51519 has not yet been referenced specifically in any publications.

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