Anti-TIM 1抗体(ab78494)


  • 产品名称Anti-TIM 1抗体
    参阅全部 TIM 1 一抗
  • 描述
    兔多克隆抗体to TIM 1
  • 经测试应用适用于: WB, IHC-Pmore details
  • 种属反应性
    与反应: Mouse, Human
  • 免疫原

    Synthetic peptide, corresponding to a portion of the amino acids 200-300 of Human TIM 1

  • 阳性对照
    • Testis tissue



Our Abpromise guarantee covers the use of ab78494 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 - 3 µg/ml. Predicted molecular weight: 39 kDa.
IHC-P Use a concentration of 2.5 - 5 µg/ml.


  • 功能May play a role in T-helper cell development and the regulation of asthma and allergic diseases. Receptor for TIMD4 (By similarity). In case of human hepatitis A virus (HHAV) infection, functions as a cell-surface receptor for the virus. May play a role in kidney injury and repair.
  • 组织特异性Widely expressed, with highest levels in kidney and testis. Expressed by activated CD4+ T-cells during the development of helper T-cells responses.
  • 序列相似性Belongs to the immunoglobulin superfamily. TIM family.
    Contains 1 Ig-like V-type (immunoglobulin-like) domain.
  • 细胞定位Membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • CD365 antibody
    • HAVCR 1 antibody
    • HAVCR antibody
    • HAVcr-1 antibody
    • Havcr1 antibody
    • Hepatitis A virus cellular receptor 1 antibody
    • Kidney injury molecule 1 antibody
    • KIM 1 antibody
    • KIM-1 antibody
    • T cell immunoglobin domain and mucin domain protein 1 antibody
    • T cell immunoglobulin mucin family member 1 antibody
    • T cell immunoglobulin mucin receptor 1 antibody
    • T-cell immunoglobulin and mucin domain-containing protein 1 antibody
    • T-cell membrane protein 1 antibody
    • TIM antibody
    • TIM-1 antibody
    • TIM1 antibody
    • TIMD 1 antibody
    • TIMD-1 antibody
    • TIMD1 antibody
    • TIMD1_HUMAN antibody
    see all

Anti-TIM 1 antibody 图像

  • Immunohistochemical analysis of Formaldehyde-fixed murine obese nephric tissue sections, labelling TIM 1 with ab78494 at a dilution of 1/2500 incubated for 12 hours at 4°C in PBS and 2.5% Horse serum. Heat mediated antigen retrival was with Citrate buffer. Blocking was with 2.5% horse serum incubated for 1 hour at 25°C. Secondary was a horse anti-rabbit polyclonal HRP conjugate used undiluted. Counterstaining against nuclear DNA was with DAPI.

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  • Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human testis tissue, staining TIM 1 with ab78494 at 5 µg/ml.
  • All lanes : Anti-TIM 1 antibody (ab78494) at 3 µg/ml

    Lane 1 : Human brain lysate
    Lane 2 : Human brain lysate in presence of immunizing peptide
    Lane 3 : Mouse brain lysate

    Predicted band size : 39 kDa

Anti-TIM 1 antibody (ab78494)参考文献

ab78494 has not yet been referenced specifically in any publications.

Product Wall

Application Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Sample Mouse Tissue sections (kidney)
Antigen retrieval step Heat mediated - Buffer/Enzyme Used: Citrate buffer 1X
Permeabilization No
Specification kidney
Blocking step Serum as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 2.5% · Temperature: 25°C
Fixative Formaldehyde

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提交于 Oct 14 2015