概述

  • 产品名称Anti-TIGAR抗体
    参阅全部 TIGAR 一抗
  • 描述
    兔多克隆抗体to TIGAR
  • 经测试应用适用于: IHC-P, IPmore details
    不适用于: WB
  • 种属反应性
    与反应: Human
    预测可用于: Chimpanzee, Rhesus monkey, Gorilla, Orangutan
  • 免疫原

    A synthetic peptide corresponding to a region between amino acids 220 and 270 of Human TIGAR (NP_065108.1)

  • 阳性对照
    • HeLa cell lysate

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液Preservative: 0.09% Sodium azide
    Constituent: 99% Tris citrate/phosphate
    Note: pH: 7 to 8
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

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应用

Our Abpromise guarantee covers the use of ab113980 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P 1/500 - 1/2000. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
IP Use at 10 µg/mg of lysate.
  • 应用说明Is unsuitable for WB.
  • 靶标

    • 功能Probable fructose-biphosphatase. Lowers cellular levels of fructose 2,6-bisphosphate. Protects cells against reactive oxygen species and against apoptosis induced by p53/TP53.
    • 序列相似性Belongs to the phosphoglycerate mutase family.
    • 翻译后修饰Phosphorylated upon DNA damage, probably by ATM or ATR.
    • Information by UniProt
    • 数据库链接
    • 别名
      • 6-bisphosphatase TIGAR antibody
      • C12ORF5 antibody
      • chromosome 12 open reading frame 5 antibody
      • FR2BP antibody
      • Fructose-2,6-bisphosphatase TIGAR antibody
      • Fructose-2,6-bisphosphate 2-phosphatase antibody
      • Probable fructose 2,6 bisphosphatase TIGAR antibody
      • Probable fructose-2 antibody
      • tigar antibody
      • TIGAR_HUMAN antibody
      • TP53 induced glycolysis and apoptosis regulator antibody
      • TP53 induced glycolysis regulatory phosphatase antibody
      • TP53-induced glycolysis and apoptosis regulator antibody
      • Transactivated by NS3TP2 protein antibody
      see all

    Anti-TIGAR antibody 图像

    • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human prostate carcinoma tissue labelling TIGAR with ab113980 at 1/1000 (1µg/ml). Detection: DAB.
    • ab113980 used for IP at 10 µg/mg lysate, staining TIGAR in HeLa whole cell lysate (1 mg for IP, 20% of IP loaded)

      Detection: Chemiluminescence with an exposure time of 30 seconds.

    Anti-TIGAR antibody (ab113980)参考文献

    ab113980 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"