概述

  • 产品名称Anti-TIAL1抗体
    参阅全部 TIAL1 一抗
  • 描述
    兔多克隆抗体to TIAL1
  • 经测试应用适用于: ICC/IF, WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Dog
  • 免疫原

    Synthetic peptide: QQGFGVDQSP SAAWMGGFGA QPPQGQAPPP VIPPPNQAGY GMASYQTQ, corresponding to a sequence within C terminal amino acids 328-375 of Human TIAL1

性能

应用

Our Abpromise guarantee covers the use of ab26257 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ICC/IF Use at an assay dependent dilution.
WB Use a concentration of 1.25 µg/ml. Predicted molecular weight: 42 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能RNA-binding protein. Possesses nucleolytic activity against cytotoxic lymphocyte target cells. May be involved in apoptosis.
  • 序列相似性Contains 3 RRM (RNA recognition motif) domains.
  • 翻译后修饰Phosphorylated by MAPK14 following DNA damage, releasing TIAR from GADD45A mRNA.
  • 细胞定位Cytoplasm. Nucleus. Cytoplasmic granule. The cytoplasmic granules are stress granules which are a dense aggregation in the cytosol composed of proteins and RNAs that appear when the cell is under stress. Colocalizes with NANOS3 in the stress granules (By similarity). Cytoplasmic granules of cytolytic T-lymphocytes.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Aging associated gene 7 protein antibody
    • Nucleolysin TIAR antibody
    • T cluster binding protein antibody
    • TCBP antibody
    • TIA 1 related nucleolysin antibody
    • TIA-1-related protein antibody
    • TIA1 cytotoxic granule associated RNA binding protein like 1 antibody
    • TIA1 related protein antibody
    • TIAL1 antibody
    • TIAR antibody
    • TIAR_HUMAN antibody
    see all

Anti-TIAL1 antibody 图像

  • Anti-TIAL1 antibody (ab26257) at 1.25 µg/ml

    Predicted band size : 42 kDa

Anti-TIAL1 antibody (ab26257)参考文献

This product has been referenced in:
  • Schäffler K  et al. A stimulatory role for the La-related protein 4B in translation. RNA 16:1488-99 (2010). ICC/IF ; Human . Read more (PubMed: 20573744) »
  • Linder B  et al. Tdrd3 is a novel stress granule-associated protein interacting with the Fragile-X syndrome protein FMRP. Hum Mol Genet 17:3236-46 (2008). Read more (PubMed: 18664458) »

See all 2 Publications for this product

Product Wall

Abcam guarantees this product to work in the species/application used in this Abreview.
Application Immunocytochemistry/ Immunofluorescence
Sample Human Cell (cos7)
Specification cos7
Fixative Formaldehyde
Permeabilization Yes - Triton
Username

Abcam user community

Verified customer

提交于 Oct 12 2010

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"