Anti-Thyroid Hormone Receptor alpha 1+2抗体, prediluted (ab15544)

概述

性能

应用

Our Abpromise guarantee covers the use of ab15544 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P
  • 应用说明IHC-P: Use at an assay dependent dilution. Staining of formalin fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0 for 10 min followed by cooling at room temperature for 20 min.

    Not tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Isoform Alpha-1: Nuclear hormone receptor that can act as a repressor or activator of transcription. High affinity receptor for thyroid hormones, including triiodothyronine and thyroxine.
      Isoform Alpha-2: Does not bind thyroid hormone and functions as a weak dominant negative inhibitor of thyroid hormone action.
    • 疾病相关Hypothyroidism, congenital, non-goitrous, 6
    • 序列相似性Belongs to the nuclear hormone receptor family. NR1 subfamily.
      Contains 1 nuclear receptor DNA-binding domain.
    • 结构域Composed of three domains: a modulating N-terminal domain, a DNA-binding domain and a C-terminal ligand-binding domain.
    • 细胞定位Nucleus.
    • Information by UniProt
    • 数据库链接
    • 别名
      • c-erbA-1 antibody
      • C-erbA-alpha antibody
      • EAR-7 antibody
      • ERBA 1 antibody
      • ERBA antibody
      • ERBA related 7 antibody
      • Nuclear receptor subfamily 1 group A member 1 antibody
      • THA_HUMAN antibody
      • THRA antibody
      • Thra1 antibody
      • Thra2 antibody
      • Thyroid hormone receptor alpha 1 antibody
      • Thyroid hormone receptor alpha 2 antibody
      • Thyroid hormone receptor alpha antibody
      • TR alpha 1 antibody
      • TR alpha 2 antibody
      • Tra1 antibody
      • Triiodothyronine receptor antibody
      • V-erbA-related protein 7 antibody
      see all

    Anti-Thyroid Hormone Receptor alpha 1+2 antibody, prediluted 图像

    • ab15544 staining thyroid hormone receptor alpha 1 and 2 in colon carcinoma by Immunohistochemistry (formalin/paraffin).

    Anti-Thyroid Hormone Receptor alpha 1+2 antibody, prediluted (ab15544)参考文献

    ab15544 has not yet been referenced specifically in any publications.

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