Anti-Thyroid Hormone Receptor alpha 1+2抗体,prediluted (ab15544)

概述

  • 产品名称
    Anti-Thyroid Hormone Receptor alpha 1+2抗体,prediluted
    参阅全部 Thyroid Hormone Receptor alpha 1+2 一抗
  • 描述
    兔多克隆抗体to Thyroid Hormone Receptor alpha 1+2,prediluted
  • 宿主
    Rabbit
  • 经测试应用
    适用于: IHC-Pmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Pig
  • 免疫原

    Synthetic peptide. This information is considered to be commercially sensitive.

  • 阳性对照
    • Colon carcinoma.

性能

应用

Our Abpromise guarantee covers the use of ab15544 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P
  • 应用说明
    IHC-P: Use at an assay dependent dilution. Staining of formalin fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0 for 10 min followed by cooling at room temperature for 20 min.

    Not tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能
      Isoform Alpha-1: Nuclear hormone receptor that can act as a repressor or activator of transcription. High affinity receptor for thyroid hormones, including triiodothyronine and thyroxine.
      Isoform Alpha-2: Does not bind thyroid hormone and functions as a weak dominant negative inhibitor of thyroid hormone action.
    • 疾病相关
      Hypothyroidism, congenital, non-goitrous, 6
    • 序列相似性
      Belongs to the nuclear hormone receptor family. NR1 subfamily.
      Contains 1 nuclear receptor DNA-binding domain.
    • 结构域
      Composed of three domains: a modulating N-terminal domain, a DNA-binding domain and a C-terminal ligand-binding domain.
    • 细胞定位
      Nucleus.
    • Information by UniProt
    • 数据库链接
    • 别名
      • c-erbA-1 antibody
      • C-erbA-alpha antibody
      • EAR-7 antibody
      • ERBA 1 antibody
      • ERBA antibody
      • ERBA related 7 antibody
      • Nuclear receptor subfamily 1 group A member 1 antibody
      • THA_HUMAN antibody
      • THRA antibody
      • Thra1 antibody
      • Thra2 antibody
      • Thyroid hormone receptor alpha 1 antibody
      • Thyroid hormone receptor alpha 2 antibody
      • Thyroid hormone receptor alpha antibody
      • TR alpha 1 antibody
      • TR alpha 2 antibody
      • Tra1 antibody
      • Triiodothyronine receptor antibody
      • V-erbA-related protein 7 antibody
      see all

    图片

    • ab15544 staining thyroid hormone receptor alpha 1 and 2 in colon carcinoma by Immunohistochemistry (formalin/paraffin).

    文献

    ab15544 has not yet been referenced specifically in any publications.

    客户评价及客户问答

    Thank you for your enquiry. Unfortunately, we don't have the corresponding peptides for these antibodies. If you cannot find what you are looking for within the Abcam catalogue, you can click on the link to "The World's Antibody Gateway". The World's ...

    Read More

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

    注册