The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Plays an important role in the organization of the cytoskeleton (By similarity). Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization. Seraspenide inhibits the entry of hematopoeitic pluripotent stem cells into the S-phase.
Expressed in several hemopoietic cell lines and lymphoid malignant cells. Decreased levels in myeloma cells.