Anti-Thymocytes抗体(ab112216)

概述

• 产品名称
  Anti-Thymocytes抗体
• 描述
  兔多克隆抗体to Thymocytes
• 特异性
  ab112216 is strongly cytotoxic to Mouse thymocytes of all strains tested. ab112216 dilution which results in 50% cytotoxicity against thymus cells: 1/40000. Treatment of C57BL/6 splenocytes with ab112216 plus complement resulted in a reduction in the number of plaque-forming cells. As assessed by a CTL assay, T cell function was essentially eliminated in both pre-sensitized and post-sensitized treated samples. These results are consistent with the removal of T helper and T cytotoxicity cell activity.
• 经测试应用
  适用于: Functional Studiesmore details
• 种属反应性
  与反应: Mouse
  
• 免疫原

  Mouse Thymocytes

• 阳性对照
  • Mouse Thymus (Tested strains: C3H/He, AKR, A.TH, A.TL, BALB/c); C57BL/6 Splenocytes

性能

• 形式
  Liquid
• 存放说明
  Shipped at 4°C. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
• 存储溶液
  Constituent: 100% Whole serum
• Concentration information loading...
• 纯度
  Preadsorbed antiserum
• 纯化说明
  Heat Inactivation: 60 minutes at 56°C Adsorption: Mouse erythrocytes/hepatocytes
• 克隆
  多克隆
• 同种型
  IgG
• 研究领域
  • Immunology
  • Adaptive Immunity
  • T Cells
  • Non-CD

相关产品

• Compatible Secondaries
  • Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (ab150077)
  • Goat Anti-Rabbit IgG H&L (HRP) (ab205718)

应用

靶标

• 相关性
  Thymocytes are T cell precursors which develop in the thymus. The processes of beta-selection, positive selection and negative selection shape thymocytes into a peripheral pool of T cells that are able to respond to foreign pathogens and are immunologically tolerant towards self antigens.
• 细胞定位
  Cell Membrane