存放说明 Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C. Stable for 12 months at -20°C.
存储溶液 PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
纯度 Tissue culture supernatant
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/1000 - 1/10000. Predicted molecular weight: 36 kDa.
1/10 - 1/100.
1/50 - 1/100. Heat up to 98 °C, below boiling, and then let cool for 10-20 min.
1/100 - 1/250.
1/10 - 1/100.
ab172730 - Rabbit monoclonal IgG, is suitable for use as an isotype control with this antibody.
功能 Contributes to the de novo mitochondrial thymidylate biosynthesis pathway.
通路 Pyrimidine metabolism; dTTP biosynthesis.
序列相似性 Belongs to the thymidylate synthase family.
细胞定位 Nucleus. Cytoplasm. Mitochondrion. Mitochondrion matrix. Mitochondrion inner membrane.
Information by UniProt
d TMP synthase antibody
EC 220.127.116.11 antibody
Anti-Thymidylate Synthase antibody [EPR4545] 图像
Western blot - Thymidylate Synthase antibody [EPR4545] (ab108995)
All lanes : Anti-Thymidylate Synthase antibody [EPR4545] (ab108995) at 1/1000 dilution Lane 1 : HeLa cell lysate Lane 2 : Jurkat cell lysate Lane 3 : HL60 cell lysate Lane 4 : MCF7 cell lysate Lysates/proteins at 10 µg per lane. Performed under reducing conditions. Predicted band size : 36 kDa
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Thymidylate Synthase antibody [EPR4545] (ab108995)
ab108995 at 1/50 dilution, staining Thymidylate Synthase in Human ovary carcinoma Immunohistochemistry, Paraffin-embedded tissue.
Anti-Thymidylate Synthase antibody [EPR4545] (ab108995)参考文献
This product has been referenced in:
et al. Slug-dependent upregulation of L1CAM is responsible for the increased invasion potential of pancreatic cancer cells following long-term 5-FU treatment. PLoS One 10:e0123684 (2015).
Read more (PubMed: 25860483) »
et al. Prognostic and therapeutic impact of argininosuccinate synthetase 1 control in bladder cancer as monitored longitudinally by PET imaging. Cancer Res 74:896-907 (2014).
Read more (PubMed: 24285724) »
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for this product
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"