Anti-Thymidine Kinase 2抗体(ab123785)

概述

  • 产品名称Anti-Thymidine Kinase 2抗体
    参阅全部 Thymidine Kinase 2 一抗
  • 描述
    兔多克隆抗体to Thymidine Kinase 2
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide conjugated to KLH, corresponding to a region within C terminal amino acids 233-263 of Human Thymidine Kinase 2 (NP_001166114.1, NP_004605.4).

  • 阳性对照
    • A549 cell line lysates.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at 4°C (up to 6 months). Store at -20°C long term.
  • 存储溶液Preservative: 0.09% Sodium azide
    Constituent: 99% PBS
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 纯化说明ab123785 is purified through a protein A column, followed by peptide affinity purification.
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

相关产品

应用

Our Abpromise guarantee covers the use of ab123785 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/100 - 1/500. Predicted molecular weight: 31 kDa.

靶标

  • 功能Deoxyribonucleoside kinase that phosphorylates thymidine, deoxycytidine, and deoxyuridine. Also phosphorylates anti-viral and anti-cancer nucleoside analogs.
  • 组织特异性Predominantly expressed in liver, pancreas, muscle, and brain.
  • 疾病相关Defects in TK2 are a cause of mitochondrial DNA depletion syndrome type 2 (MTDPS2) [MIM:609560]. A disorder characterized primarily by childhood onset of muscle weakness associated with depletion of mtDNA in skeletal muscle. There is wide clinical variability; some patients have onset in infancy and show a rapidly progressive course with early death due to respiratory failure, whereas others have later onset of a slowly progressive myopathy.
  • 序列相似性Belongs to the DCK/DGK family.
  • 细胞定位Mitochondrion.
  • Information by UniProt
  • 数据库链接
  • 别名
    • EC 2.7.1.21 antibody
    • KITM_HUMAN antibody
    • mitochondrial antibody
    • Mt TK antibody
    • Mt-TK antibody
    • Thymidine kinase 2 antibody
    • Thymidine kinase 2 mitochondrial antibody
    • TK2 antibody
    see all

Anti-Thymidine Kinase 2 antibody 图像

  • Anti-Thymidine Kinase 2 antibody (ab123785) at 1/100 dilution + A549 cell line lysates at 35 µg

    Predicted band size : 31 kDa

Anti-Thymidine Kinase 2 antibody (ab123785)参考文献

ab123785 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab123785.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"