Anti-Thromboxane A2 receptor抗体(ab92883)

概述

  • 产品名称Anti-Thromboxane A2 receptor抗体
    参阅全部 Thromboxane A2 receptor 一抗
  • 描述
    兔多克隆抗体to Thromboxane A2 receptor
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Mouse, Rat, Human
    预测可用于: Cow
  • 免疫原

    Synthetic peptide:

    LSTRPRSLSLQPQLTQRSGLQ

    , corresponding to amino acids 323-343 of Human Thromboxane A2 receptor.

  • 阳性对照
    • Jurkat, ECL, SGC cell lysates

性能

相关产品

应用

Our Abpromise guarantee covers the use of ab92883 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
  • 应用说明WB: 1/500 - 1/5000. Detects a band of approximately 55 kDa (predicted molecular weight: 40 kDa).


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Receptor for thromboxane A2 (TXA2), a potent stimulator of platelet aggregation. The activity of this receptor is mediated by a G-protein that activates a phosphatidylinositol-calcium second messenger system. In the kidney, the binding of TXA2 to glomerular TP receptors causes intense vasoconstriction. Activates phospholipase C. Isoform 1 activates adenylyl cyclase. Isoform 2 inhibits adenylyl cyclase.
    • 疾病相关Defects in TBXA2R are the cause of susceptibility to bleeding disorder platelet-type 13 (BDPLT13) [MIM:614009]. BDPLT13 is a disorder characterized by reduced platelet aggregation and a tendency to mild mucocutaneous bleeding.
    • 序列相似性Belongs to the G-protein coupled receptor 1 family.
    • 细胞定位Cell membrane.
    • Information by UniProt
    • 数据库链接
    • 别名
      • BDPLT13 antibody
      • Prostanoid TP receptor antibody
      • TA2R_HUMAN antibody
      • Tbxa2r antibody
      • Thromboxane A2 receptor antibody
      • TP receptor antibody
      • TXA2 R antibody
      • TXA2-R antibody
      • TXA2R antibody
      see all

    Anti-Thromboxane A2 receptor antibody 图像

    • All lanes : Anti-Thromboxane A2 receptor antibody (ab92883) at 1/1000 dilution

      Lane 1 : Jurkat cell lysate at 43 µg
      Lane 2 : ECL cell lysate at 67 µg
      Lane 3 : SGC cell lysate at 55 µg


      Predicted band size : 40 kDa
      Observed band size : 55 kDa (why is the actual band size different from the predicted?)

    Anti-Thromboxane A2 receptor antibody (ab92883)参考文献

    ab92883 has not yet been referenced specifically in any publications.

    Product Wall

    Thank you for contacting us. We do not currently have any Thromboxone A2 receptor proteins or peptides in our catalog.

    I hope this information is helpful to you. Please do not hesitate to contact us if you need any more advice or information.<...

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    Thank you for contacting us. Yes, this antibody can be used with mouse samples. The other anti-Thromboxane A2 receptor antibody (ab85544) has not been tested with mouse. We are currently not aware of any publications or references that have used the an...

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"