Anti-Thrombospondin抗体[A65M] (ab23420)

概述

  • 产品名称Anti-Thrombospondin抗体[A65M]
    参阅全部 Thrombospondin 一抗
  • 描述
    小鼠单克隆抗体[A65M] to Thrombospondin
  • 特异性ab23420 is highly specific for the low-calcium conformation of thrombospondin. There is no cross-reactivity with other connective tissue proteins (vitronectin, fibronectin, elastin, collagen, laminin).
  • 经测试应用适用于: IP, IHC-Fr, ELISAmore details
  • 种属反应性
    与反应: Cow, Human
  • 免疫原

    Corneal endothelial cells on beads (Cow).

  • 表位Epitope is only present in thrombospondin prepared with low levels of calcium

性能

应用

Our Abpromise guarantee covers the use of ab23420 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IP Use at an assay dependent concentration.
IHC-Fr 1/40. PLP-fixed sections of bovine and human tissues.
ELISA 1/200.

靶标

  • 功能Adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions.
  • 序列相似性Belongs to the thrombospondin family.
    Contains 3 EGF-like domains.
    Contains 1 TSP C-terminal (TSPC) domain.
    Contains 1 TSP N-terminal (TSPN) domain.
    Contains 3 TSP type-1 domains.
    Contains 8 TSP type-3 repeats.
    Contains 1 VWFC domain.
  • Information by UniProt
  • 数据库链接
  • 别名
    • THBS 1 antibody
    • THBS antibody
    • Thbs1 antibody
    • Thrombospondin 1 antibody
    • Thrombospondin-1 antibody
    • TSP 1 antibody
    • TSP antibody
    • TSP1 antibody
    • TSP1_HUMAN antibody
    see all

Anti-Thrombospondin antibody [A65M] (ab23420)参考文献

This product has been referenced in:
  • He J & Bazan HE Epidermal growth factor synergism with TGF-beta1 via PI-3 kinase activity in corneal keratocyte differentiation. Invest Ophthalmol Vis Sci 49:2936-45 (2008). Read more (PubMed: 18579759) »
  • Behera MA  et al. Thrombospondin-1 and thrombospondin-2 mRNA and TSP-1 and TSP-2 protein expression in uterine fibroids and correlation to the genes COL1A1 and COL3A1 and to the collagen cross-link hydroxyproline. Reprod Sci 14:63-76 (2007). Read more (PubMed: 18089612) »

See all 2 Publications for this product

Product Wall

Thank you for your patience. I have been in correspondence with the source of each of the antibodies. Unfortunately PTP4A1 antibody (ab22825) is a fast track antibody and has not been applied to a positive control as such. ab23420 has not been ...

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Thank you for your enquiry. I am sorry to hear that you have been having difficulties with this antibody. PTP4A1 antibody (ab22825) is currently a fast track antibody that we cannot guarantee for the application of western blotting. We appreciat...

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Thank you for your enquiry. Ab23420 has only so far been tested for application in IHC-frozen tissue sections. It has not yet been tested with paraffin embedded sections. If you decide to go ahead and purchase this product, please let us know how yo...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"