Anti-Thrombopoietin抗体(Biotin) (ab84445)

概述

  • 产品名称
    Anti-Thrombopoietin抗体(Biotin)
    参阅全部 Thrombopoietin 一抗
  • 描述
    山羊多克隆抗体to Thrombopoietin (Biotin)
  • 偶联物
    Biotin
  • 经测试应用
    适用于: ELISA, Sandwich ELISA, WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Highly pure (>98%) recombinant Human full length protein

性能

应用

Our Abpromise guarantee covers the use of ab84445 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA Use a concentration of 0.25 - 1 µg/ml. Detection limit for recombinant Human Thrombopoietin: 0.2 - 0.4 ng/well.
Sandwich ELISA Use a concentration of 0.25 - 1 µg/ml. Use as detection antibody with recommended pair. Detection of recombinant Human Thrombopoietin: 0.2 - 0.4 ng/well.
WB Use a concentration of 0.1 - 0.2 µg/ml. Predicted molecular weight: 38 kDa. Detection limit for recombinant Human Thrombopoietin: 1.5 - 3.0 ng/lane, under reducing or non-reducing conditions.

靶标

  • 功能
    Lineage-specific cytokine affecting the proliferation and maturation of megakaryocytes from their committed progenitor cells. It acts at a late stage of megakaryocyte development. It may be the major physiological regulator of circulating platelets.
  • 疾病相关
    Defects in THPO are a cause of essential thrombocythemia (ET) [MIM:187950]. ET is inherited as an autosomal dominant trait which is characterized by elevated platelet levels due to sustained proliferation of megakaryocytes, and frequently lead to thrombotic and haemorrhagic complications.
  • 序列相似性
    Belongs to the EPO/TPO family.
  • 结构域
    Two-domain structure with an erythropoietin-like N-terminal and a Ser/Pro/Thr-rich C-terminal.
  • 细胞定位
    Secreted.
  • Information by UniProt
  • 数据库链接
  • 别名
    • C mpl ligand antibody
    • C-mpl ligand antibody
    • Megakaryocyte colony stimulating factor antibody
    • Megakaryocyte colony-stimulating factor antibody
    • Megakaryocyte growth and development factor antibody
    • Megakaryocyte stimulating factor antibody
    • MGC163194 antibody
    • MGDF antibody
    • MKCSF antibody
    • ML antibody
    • MPL ligand antibody
    • MPLLG antibody
    • Myeloproliferative leukemia virus oncogene ligand antibody
    • Prepro thrombopoietin antibody
    • THCYT1 antibody
    • THPO antibody
    • Thrombopoietin antibody
    • Thrombopoietin nirs variant 1 antibody
    • TPO antibody
    • TPO_HUMAN antibody
    see all

实验方案

文献

ab84445 has not yet been referenced specifically in any publications.

客户评价及客户问答

There are currently no Customer reviews or Questions for ab84445.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

注册