Anti-Thrombin Receptor抗体, prediluted (ab32612)

概述

  • 产品名称Anti-Thrombin Receptor抗体, prediluted
    参阅全部 Thrombin Receptor 一抗
  • 描述
    兔多克隆抗体to Thrombin Receptor, prediluted
  • 经测试应用适用于: IHC-Pmore details
  • 种属反应性
    与反应: Human
    预测可用于: Baboon
  • 免疫原

    Synthetic peptide:

    SFLLRNPND KYEPF

    , corresponding to amino acids 42-55 of Human Thrombin Receptor.

  • 阳性对照
    • KNRK cells, human pancreas.

性能

相关产品

应用

Our Abpromise guarantee covers the use of ab32612 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P Use at an assay dependent concentration. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.

靶标

  • 功能High affinity receptor for activated thrombin coupled to G proteins that stimulate phosphoinositide hydrolysis. May play a role in platelets activation and in vascular development.
  • 组织特异性Platelets and vascular endothelial cells.
  • 序列相似性Belongs to the G-protein coupled receptor 1 family.
  • 翻译后修饰A proteolytic cleavage generates a new N-terminus that functions as a tethered ligand.
    Phosphorylated; probably mediating desensitization prior to the uncoupling and internalization of the receptor.
  • 细胞定位Cell membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • CF2R antibody
    • Coagulation factor II (thrombin) receptor antibody
    • Coagulation factor II receptor antibody
    • F2R antibody
    • HTR antibody
    • PAR 1 antibody
    • PAR-1 antibody
    • PAR1 antibody
    • PAR1_HUMAN antibody
    • Protease activated receptor 1 antibody
    • Proteinase activated receptor 1 antibody
    • Proteinase-activated receptor 1 antibody
    • Thrombin receptor antibody
    • TR antibody
    see all

Anti-Thrombin Receptor antibody, prediluted 图像

  • Ab32012, prediluted, staining Thrombin Receptor in formalin fixed paraffin embedded human pancreas tissue sections by Immunohistochemistry.

Anti-Thrombin Receptor antibody, prediluted (ab32612)参考文献

ab32612 has not yet been referenced specifically in any publications.

Product Wall

Abcam guarantees this product to work in the species/application used in this Abreview.
Application Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Sample Human Tissue sections (pancreas)
Specification pancreas
Fixative Formaldehyde
Antigen retrieval step Heat mediated - Buffer/Enzyme Used: pH 6.0
Permeabilization No
Blocking step Serum as blocking agent for 10 minute(s) · Concentration: 10%
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提交于 Feb 26 2009

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"