Anti-Thrombin Receptor抗体(ab87647)

概述

  • 产品名称Anti-Thrombin Receptor抗体
    参阅全部 Thrombin Receptor 一抗
  • 描述
    山羊多克隆抗体to Thrombin Receptor
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide with sequence

    C-TRARRPESKATNAT

    , corresponding to internal sequence (near the N terminus) amino acids 24 - 37 of Human Thrombin Receptor, with a Cysteine residue linker (NP_001983.2.)

  • 阳性对照
    • HeLa cell lysate

性能

相关产品

应用

Our Abpromise guarantee covers the use of ab87647 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 0.5 - 2 µg/ml. Predicted molecular weight: 47 kDa.

靶标

  • 功能High affinity receptor for activated thrombin coupled to G proteins that stimulate phosphoinositide hydrolysis. May play a role in platelets activation and in vascular development.
  • 组织特异性Platelets and vascular endothelial cells.
  • 序列相似性Belongs to the G-protein coupled receptor 1 family.
  • 翻译后修饰A proteolytic cleavage generates a new N-terminus that functions as a tethered ligand.
    Phosphorylated; probably mediating desensitization prior to the uncoupling and internalization of the receptor.
  • 细胞定位Cell membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • CF2R antibody
    • Coagulation factor II (thrombin) receptor antibody
    • Coagulation factor II receptor antibody
    • F2R antibody
    • HTR antibody
    • PAR 1 antibody
    • PAR-1 antibody
    • PAR1 antibody
    • PAR1_HUMAN antibody
    • Protease activated receptor 1 antibody
    • Proteinase activated receptor 1 antibody
    • Proteinase-activated receptor 1 antibody
    • Thrombin receptor antibody
    • TR antibody
    see all

Anti-Thrombin Receptor antibody 图像

  • Anti-Thrombin Receptor antibody (ab87647) at 0.5 µg/ml + HeLa cell lysate (in RIPA buffer) at 35 µg
    Developed using the ECL technique

    Predicted band size : 47 kDa
    Observed band size : 47 kDa

Anti-Thrombin Receptor antibody (ab87647)参考文献

ab87647 has not yet been referenced specifically in any publications.

Product Wall

Thank you for your enquiry regarding ab87647.

I can confirm that the immunogen used to raise is a synthetic peptide with sequence C-TRARRPESKATNAT, corresponding to internal sequence (near the N terminus) amino acids 24 - 37 of Human Thrombin...

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The Uniprot http://www.uniprot.org/uniprot/P25116 database shows, the active part of protein "human Proteinase-activated receptor 1" has amino acid sequence between 42-425, so antibodies specific to this ...

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