概述

  • 产品名称Anti-THEM4抗体
    参阅全部 THEM4 一抗
  • 描述
    兔多克隆抗体to THEM4
  • 经测试应用适用于: ICC/IF, IHC-P, WBmore details
  • 种属反应性
    与反应: Mouse, Rat, Human
  • 免疫原

    18 amino acid synthetic peptide designed near the center of Human THEM4 (NP_444283).

  • 阳性对照
    • Human liver tissue / tissue lysate.

性能

应用

Our Abpromise guarantee covers the use of ab106435 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ICC/IF Use a concentration of 20 µg/ml.
IHC-P Use a concentration of 2.5 µg/ml.
WB Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 27 kDa.

靶标

  • 功能According to PubMed:11598301, inhibits AKT1 phosphorylation and activity. According to PubMed:17615157, enhances AKT1 activity by favoring its phosphorylation and translocation to plasma membrane.
  • 组织特异性Expressed predominantly in skeletal muscle, testis, uterus, brain and kidney. Down-regulated in glioblastoma or glioma compared to non-neoplastic brain due to promoter hypermethylation.
  • 翻译后修饰Phosphorylated.
  • 细胞定位Cell membrane. Cell projection > ruffle membrane. Cytoplasm.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Acyl CoA thioesterase THEM4 antibody
    • Acyl coenzyme A thioesterase THEM4 antibody
    • C terminal modulator protein antibody
    • Carboxyl-terminal modulator protein antibody
    • CTMP antibody
    • FLJ27206 antibody
    • MGC29636 antibody
    • OTTHUMP00000015248 antibody
    • Them4 antibody
    • THEM4_HUMAN antibody
    • Thioesterase superfamily member 4 antibody
    see all

Anti-THEM4 antibody 图像

  • Immunofluorescence of THEM4 in Human liver tissue with ab106435 at 20 ug/mL.

  • Lane 1 : Anti-THEM4 antibody (ab106435) at 1 µg/ml
    Lane 2 : Anti-THEM4 antibody (ab106435) at 2 µg/ml

    Lane 1 : Human liver tissue lysate
    Lane 2 : Human liver tissue lysate

    Lysates/proteins at 15 µg per lane.


    Predicted band size : 27 kDa
  • ab106435 at 2.5µg staining THEM4 in paraffin embedded Human liver tissue by immunohistochemistry.

Anti-THEM4 antibody (ab106435)参考文献

ab106435 has not yet been referenced specifically in any publications.

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