Anti-TGFBRAP1抗体(ab220084)
Key features and details
- Rabbit polyclonal to TGFBRAP1
- Suitable for: WB, ICC/IF
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-TGFBRAP1抗体
参阅全部 TGFBRAP1 一抗 -
描述
兔多克隆抗体to TGFBRAP1 -
宿主
Rabbit -
经测试应用
适用于: WB, ICC/IFmore details -
种属反应性
与反应: Human
预测可用于: Mouse, Cow -
免疫原
Recombinant fragment corresponding to Human TGFBRAP1 aa 450-600.
Database link: Q8WUH2 -
阳性对照
- RT-4 cell lysate and human tonsil tissue lysate; A431 cells
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
存储溶液
pH: 7.20
Preservative: 0.02% Sodium azide
Constituents: 59% PBS, 40% Glycerol (glycerin, glycerine) -
Concentration information loading...
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纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab220084于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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WB |
Use a concentration of 0.04 - 0.4 µg/ml. Predicted molecular weight: 97 kDa.
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ICC/IF |
Use a concentration of 0.25 - 2 µg/ml.
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说明 |
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WB
Use a concentration of 0.04 - 0.4 µg/ml. Predicted molecular weight: 97 kDa. |
ICC/IF
Use a concentration of 0.25 - 2 µg/ml. |
靶标
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功能
Plays a role in the TGF-beta/activin signaling pathway. It associates with inactive heteromeric TGF-beta and activin receptor complexes, mainly through the type II receptor, and is released upon activation of signaling. May recruit SMAD4 to the vicinity of the receptor complex and facilitate its interaction with receptor-regulated Smads, such as SMAD2. -
序列相似性
Belongs to the TRAP1 family.
Contains 1 CNH domain. -
细胞定位
Cytoplasm. Colocalizes with TGF-beta receptors in the absence of signaling. - Information by UniProt
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数据库链接
- Entrez Gene: 9392 Human
- Entrez Gene: 73122 Mouse
- Omim: 606237 Human
- SwissProt: Q8WUH2 Human
- SwissProt: Q3UR70 Mouse
- Unigene: 446350 Human
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别名
- TGF-beta receptor-associated protein 1 antibody
- TGFA1_HUMAN antibody
- Tgfbrap1 antibody
see all
图片
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All lanes : Anti-TGFBRAP1 antibody (ab220084) at 1/100 dilution
Lane 1 : RT-4 cell lysate
Lane 2 : U-251 MG cell lysate
Lane 3 : Human plasma lysate
Lane 4 : Human liver tissue lysate
Lane 5 : Human tonsil tissue lysate
Predicted band size: 97 kDa -
Immunofluorescent analysis of PFA, triton X-100 permeabilized A431 cells labeling TGFBRAP1 using ab220084 at 4 μg/mL (green).
实验方案
数据表及文件
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SDS download
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Datasheet download
文献 (2)
ab220084 被引用在 2 文献中.
- Han YL et al. Downregulation of microRNA-193-3p inhibits the progression of intrahepatic cholangiocarcinoma cells by upregulating TGFBR3. Exp Ther Med 15:4508-4514 (2018). PubMed: 29725386
- Li Q et al. Exosomal miR-21-5p derived from gastric cancer promotes peritoneal metastasis via mesothelial-to-mesenchymal transition. Cell Death Dis 9:854 (2018). PubMed: 30154401