Anti-TGF-beta receptor-associated protein 1抗体(ab122468)

概述

  • 产品名称Anti-TGF-beta receptor-associated protein 1抗体
    参阅全部 TGF-beta receptor-associated protein 1 一抗
  • 描述
    兔多克隆抗体to TGF-beta receptor-associated protein 1
  • 经测试应用适用于: IHC-P, WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant fragment corresponding to Human TGF-beta receptor-associated protein 1 aa 712-807 (internal sequence).
    Sequence:

    RQQLFHTLLAIYLHAGPTAHELAVAAVDLLNRHATEFDAAQVLQMLPDTW SVQLLCPFLMGAMRDSIHARRTMQVALGLARSENLIYTYDKMKLKG

  • 阳性对照
    • Human pancreas tissue; RT 4 and U 251 MG cell lysates.

性能

应用

Our Abpromise guarantee covers the use of ab122468 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P 1/10 - 1/20. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
WB 1/250 - 1/500.

靶标

  • 功能Plays a role in the TGF-beta/activin signaling pathway. It associates with inactive heteromeric TGF-beta and activin receptor complexes, mainly through the type II receptor, and is released upon activation of signaling. May recruit SMAD4 to the vicinity of the receptor complex and facilitate its interaction with receptor-regulated Smads, such as SMAD2.
  • 序列相似性Belongs to the TRAP1 family.
    Contains 1 CNH domain.
  • 细胞定位Cytoplasm. Colocalizes with TGF-beta receptors in the absence of signaling.
  • Information by UniProt
  • 数据库链接
  • 别名
    • TGF-beta receptor-associated protein 1 antibody
    • TGFA1_HUMAN antibody
    • Tgfbrap1 antibody
    • Transforming growth factor-beta receptor-associated protein 1 antibody
    • TRAP-1 antibody
    • TRAP1 antibody
    • VPS3 antibody
    see all

Anti-TGF-beta receptor-associated protein 1 antibody 图像

  • ab122468, at 1/10 dilution, staining TGF-beta receptor-associated protein 1 in paraffin-embedded Human pancreas tissue by Immunohistochemistry.

  • All lanes : Anti-TGF-beta receptor-associated protein 1 antibody (ab122468) at 1/250 dilution

    Lane 1 : RT 4 cell lysate
    Lane 2 : U 251 MG cell lysate
    Lane 3 : Human plasma lysate
    Lane 4 : Human liver tissue lysate
    Lane 5 : Human tonsil tissue lysate

    Developed using the ECL technique

Anti-TGF-beta receptor-associated protein 1 antibody (ab122468)参考文献

ab122468 has not yet been referenced specifically in any publications.

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