Anti-TGF beta induced factor 2抗体(ab39998)

概述

  • 产品名称Anti-TGF beta induced factor 2抗体
    参阅全部 TGF beta induced factor 2 一抗
  • 描述
    山羊多克隆抗体to TGF beta induced factor 2
  • 经测试应用适用于: WB, ELISAmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Cow, Dog
  • 免疫原

    Synthetic peptide:

    EMELQKQQDP

    , corresponding to C terminal amino acids 211-220 of Human TGF beta induced factor 2

  • 阳性对照
    • A431, A549 and HEK293 cell lysates

性能

应用

Our Abpromise guarantee covers the use of ab39998 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 0.3 - 1 µg/ml. Detects a band of approximately 22 kDa (predicted molecular weight: 26 kDa).
ELISA 1/16000.

靶标

  • 功能Transcriptional repressor, which probably repress transcription by binding directly the 5'-CTGTCAA-3' DNA sequence or by interacting with TGF-beta activated SMAD proteins. Probably represses transcription via the recruitment of histone deacetylase proteins.
  • 组织特异性Widely expressed. Highly expressed in heart, kidney and testis. Weakly expressed in brain and prostate.
  • 序列相似性Belongs to the TALE/TGIF homeobox family.
    Contains 1 homeobox DNA-binding domain.
  • 翻译后修饰The C-terminal part is phosphorylated in response to EGF signaling by the Ras/MAPK pathway.
  • 细胞定位Nucleus. Excluded from nucleoli.
  • Information by UniProt
  • 数据库链接
  • 别名
    • 5' TG 3' interacting factor 2 antibody
    • 5''-TG-3''-interacting factor 2 antibody
    • Homeobox protein TGIF2 antibody
    • TGF (beta) induced transcription factor 2 antibody
    • TGF-beta-induced transcription factor 2 antibody
    • TGFB induced factor 2 antibody
    • TGFB-induced factor 2 antibody
    • Tgif2 antibody
    • TGIF2_HUMAN antibody
    • Transforming growth factor beta induced factor 2 antibody
    see all

Anti-TGF beta induced factor 2 antibody 图像

Anti-TGF beta induced factor 2 antibody (ab39998)参考文献

ab39998 has not yet been referenced specifically in any publications.

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