Anti-TGF beta 2抗体(ab167655)
Key features and details
- Mouse polyclonal to TGF beta 2
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-TGF beta 2抗体
参阅全部 TGF beta 2 一抗 -
描述
小鼠多克隆抗体to TGF beta 2 -
宿主
Mouse -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Human
预测可用于: Rabbit, Horse, Cow, Dog, Chimpanzee, Rhesus monkey -
免疫原
Recombinant full length protein, corresponding to amino acids 1-414 of Human TGF beta 2 (AAH99635.1).
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阳性对照
- TGF beta 2 transfected 293T cell lysate
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. -
存储溶液
pH: 7.4
Constituent: 100% PBS -
Concentration information loading...
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纯度
Protein A purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab167655于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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WB |
Use a concentration of 1 µg/ml. Predicted molecular weight: 48 kDa.
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说明 |
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WB
Use a concentration of 1 µg/ml. Predicted molecular weight: 48 kDa. |
靶标
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功能
TGF-beta 2 has suppressive effects on interleukin-2 dependent T-cell growth. -
疾病相关
A chromosomal aberration involving TGFB2 is found in a family with Peters anomaly. Translocation t(1;7)(q41;p21) with HDAC9.
Loeys-Dietz syndrome 4
Defects in TGFB2 may be a cause of non-syndromic aortic disease (NSAD). NSAD is a frequently asymptomatic but potentially lethal disease characterized by thoracic aortic aneurysms and dissections without additional syndromic features. -
序列相似性
Belongs to the TGF-beta family. -
翻译后修饰
The precursor is cleaved into mature TGF-beta-2 and LAP, which remains non-covalently linked to mature TGF-beta-2 rendering it inactive. -
细胞定位
Secreted. - Information by UniProt
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数据库链接
- Entrez Gene: 534069 Cow
- Entrez Gene: 7040 Human
- Entrez Gene: 7042 Human
- Entrez Gene: 7043 Human
- Entrez Gene: 100009371 Rabbit
- Omim: 190220 Human
- SwissProt: P21214 Cow
- SwissProt: P01137 Human
see all -
别名
- BSC-1 cell growth inhibitor antibody
- BSC1 cell growth inhibitor antibody
- Cetermin antibody
see all
图片
数据表及文件
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Datasheet download
文献 (3)
ab167655 被引用在 3 文献中.
- Song L et al. Phytosterol esters attenuate hepatic steatosis in rats with non-alcoholic fatty liver disease rats fed a high-fat diet. Sci Rep 7:41604 (2017). WB ; Rat . PubMed: 28169366
- Zhuang R et al. CR6-interacting factor 1 inhibits invasiveness by suppressing TGF-ß-mediated epithelial-mesenchymal transition in hepatocellular carcinoma. Oncotarget 8:94759-94768 (2017). PubMed: 29212264
- Liu Y et al. RUNX3 modulates hypoxia-induced endothelial-to-mesenchymal transition of human cardiac microvascular endothelial cells. Int J Mol Med 40:65-74 (2017). PubMed: 28534977