概述

  • 产品名称Anti-TFIIA2抗体
    参阅全部 GTF2A2 一抗
  • 描述
    小鼠多克隆抗体to GTF2A2
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Chicken, Cow, Xenopus laevis
  • 免疫原

    Recombinant fragment: TLGNSLQESL DELIQSQQIT PQLALQVLLQ FDKAINAALA QRVRNRVNFR GSLNTYRFCD NVWTFVLNDV EFREVTELIK VDKVKIVACD GKNTGSNTTE , corresponding to amino acids 10-109 of Human GTF2A2

  • 常规说明


    This antibody was raised by a genetic immunization technique. Genetic immunization can be used to generate antibodies by directly delivering antigen-coding DNA into the animal, rather than injecting a protein or peptide (Tang et al. PubMed: 1545867; Chambers and Johnston PubMed 12910245; Barry and Johnston PubMed: 9234514). The animal's cells produce the protein, which stimulates the animal's immune system to produce antibodies against that particular protein. A vector coding for a partial fusion protein was used for genetic immunisation of a mouse and the resulting serum was tested in Western blot against an E.coli lysate containing that partial fusion protein. Genetic immunization offers enormous advantages over the traditional protein-based immunization method. DNA is faster, cheaper and easier to produce and can be produced by standard techniques readily amenable to automation. Furthermore, the antibodies generated by genetic immunization are usually of superior quality with regard to specificity, affinity and recognizing the native protein.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
  • 存储溶液Preservative: None
    Constituents: 50% Glycerol, Whole serum
  • 纯度Whole antiserum
  • Primary antibody说明This antibody was raised by a genetic immunization technique. Genetic immunization can be used to generate antibodies by directly delivering antigen-coding DNA into the animal, rather than injecting a protein or peptide (Tang et al. PubMed: 1545867; Chambers and Johnston PubMed 12910245; Barry and Johnston PubMed: 9234514). The animal's cells produce the protein, which stimulates the animal's immune system to produce antibodies against that particular protein. A vector coding for a partial fusion protein was used for genetic immunisation of a mouse and the resulting serum was tested in Western blot against an E.coli lysate containing that partial fusion protein. Genetic immunization offers enormous advantages over the traditional protein-based immunization method. DNA is faster, cheaper and easier to produce and can be produced by standard techniques readily amenable to automation. Furthermore, the antibodies generated by genetic immunization are usually of superior quality with regard to specificity, affinity and recognizing the native protein.
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab43405 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/1000. Predicted molecular weight: 12 kDa.

This antibody has been tested in Western blot against an E.coli lysate containing the partial recombinant fusion protein used as an immunogen. We have no data on detection of endogenous protein.

靶标

  • 功能TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation. TFIIA in a complex with TBP mediates transcriptional activity.
  • 序列相似性Belongs to the TFIIA subunit 2 family.
  • 细胞定位Nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • General transcription factor IIA antibody
    • General transcription factor IIA subunit 2 antibody
    • General transcription factor IIA, 2 (12kD subunit) antibody
    • General transcription factor IIA, 2, 12kDa antibody
    • gtf2a2 antibody
    • HsT18745 antibody
    • T2AG_HUMAN antibody
    • TF2A2 antibody
    • TFIIA 12 antibody
    • TFIIA antibody
    • TFIIA gamma antibody
    • TFIIA p12 subunit antibody
    • TFIIA-12 antibody
    • TFIIA-gamma antibody
    • TFIIA12 antibody
    • TFIIAS antibody
    • Transcription initiation factor IIA gamma chain antibody
    • Transcription initiation factor IIA subunit 2 antibody
    see all

Anti-TFIIA2 antibody (ab43405)参考文献

ab43405 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab43405.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"