Anti-Tetanus Toxin抗体[TetE3] (ab64755)

概述

  • 产品名称Anti-Tetanus Toxin抗体[TetE3]
    参阅全部 Tetanus Toxin 一抗
  • 描述
    小鼠单克隆抗体[TetE3] to Tetanus Toxin
  • 经测试应用适用于: Neutralising, WB, ELISAmore details
  • 种属反应性
    Reacts with Clostridium tetani.
  • 免疫原

    Supernatant from C. tetani.

性能

应用

Our Abpromise guarantee covers the use of ab64755 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
Neutralising
WB
ELISA
  • 应用说明ELISA: Use at an assay dependent dilution.
    Neutralising activity, in vivo assay: Use at an assay dependent dilution.
    WB: Use at an assay dependent dilution. Predicted molecular weight (precursor): 151 kDa.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 相关性Tetanus toxin acts by inhibiting neurotransmitter release. It binds to peripheral neuronal synapses, is internalized and moves by retrograde transport up the axon into the spinal cord where it can move between postsynaptic and presynaptic neurons. It inhibits neurotransmitter release by acting as a zinc endopeptidase that catalyzes the hydrolysis of the 76-Gln-|-Phe-77 bond of synaptobrevin-2. The precursor polypeptide is subsequently cleaved to yield subchains L and H. These remain linked by a disulfide bridge and are non-toxic after separation.
    • 细胞定位Secreted
    • 别名
      • Tentoxylysin antibody
      • Tetanus toxin chain H antibody
      • Tetanus toxin chain L antibody
      • Tetanus toxin heavy chain antibody
      • Tetanus toxin light chain antibody
      see all

    Anti-Tetanus Toxin antibody [TetE3] (ab64755)参考文献

    This product has been referenced in:
    • Kalb SR  et al. Extraction of BoNT/A, /B, /E, and /F with a single, high affinity monoclonal antibody for detection of botulinum neurotoxin by Endopep-MS. PLoS One 5: (2010). Read more (PubMed: 20808925) »

    See 1 Publication for this product

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    Application IHC - Wholemount
    Sample Mouse Tissue (Retina slice)
    Specification Retina slice
    Username

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    提交于 Jun 04 2012

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"