概述

  • 产品名称Anti-TEM7抗体
    参阅全部 TEM7 一抗
  • 描述
    兔多克隆抗体to TEM7
  • 经测试应用适用于: WB, ELISAmore details
  • 种属反应性
    与反应: Rat, Human
    预测可用于: Mouse
  • 免疫原

    KLH conjugated synthetic peptide corresponding to a 16 amino acid sequence near the center of Human TEM7.

  • 阳性对照
    • Human kidney tissue; Rat liver lysate

性能

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应用

Our Abpromise guarantee covers the use of ab118874 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 0.5 - 1 µg/ml. Predicted molecular weight: 56 kDa.
ELISA Use at an assay dependent dilution.

靶标

  • 功能Plays a critical role in endothelial cell capillary morphogenesis.
  • 组织特异性Detected in endothelial cells from colorectal cancer, and in endothelial cells from primary cancers of the lung, liver, pancreas, breast and brain. Not detectable in endothelial cells from normal tissue. Expressed in fibrovascular membrane with increased expression in individuals with proliferative diabetic retinopathy.
  • 序列相似性Belongs to the plexin family.
  • 翻译后修饰N-glycosylated.
  • 细胞定位Cytoplasm; Secreted and Cell membrane. Cell junction > tight junction. Localized predominantly at the tight junctions of vascular endothelial cells and to a lesser extent at the luminal surface of vascular endothelial cells.
  • Information by UniProt
  • 数据库链接
  • 别名
    • DKFZp686F0937 antibody
    • FLJ36270 antibody
    • FLJ45632 antibody
    • OTTHUMP00000164240 antibody
    • Plexin domain containing 1 antibody
    • Plexin domain containing protein 1 precursor antibody
    • Plexin domain-containing protein 1 antibody
    • Plxdc1 antibody
    • PXDC1_HUMAN antibody
    • TEM3 antibody
    • TEM7 antibody
    • Tumor endothelial marker 3 antibody
    • Tumor endothelial marker 7 antibody
    see all

Anti-TEM7 antibody 图像

  • Lane 1 : Anti-TEM7 antibody (ab118874) at 0.5 µg/ml
    Lane 2 : Anti-TEM7 antibody (ab118874) at 1 µg/ml

    Lane 1 : Rat liver lysate
    Lane 2 : Rat liver lysate


    Predicted band size : 56 kDa
  • ab118874, at 5 µg/ml, staining TEM7 in formalin fixed, paraffin embedded Human kidney tissue by Immunohistochemistry. This was followed by biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.

Anti-TEM7 antibody (ab118874)参考文献

ab118874 has not yet been referenced specifically in any publications.

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