概述

  • 产品名称Anti-TEM1抗体
    参阅全部 TEM1 一抗
  • 描述
    兔多克隆抗体to TEM1
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Mouse
    预测可用于: Human
  • 免疫原

    Synthetic peptide conjugated to KLH derived from within residues 50 - 150 of Human TEM1.

    (Peptide available as ab48184.)

  • 阳性对照
    • This antibody gave a positive signal in the following Mouse Tissue Lysates: Skeletal Muscle and Heart

性能

应用

Our Abpromise guarantee covers the use of ab48185 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Detects a band of approximately 92 kDa (predicted molecular weight: 80 kDa).

靶标

  • 功能May play a role in tumor angiogenesis.
  • 组织特异性Expressed in tumor endothelial cells but absent or barely detectable in normal endothelial cells. Expressed in metastatic lesions of the liver and during angiogenesis of corpus luteum formation and wound healing. Expressed in vascular endothelial cells of malignant tumors but not in normal blood vessels. Expressed in stromal fibroblasts.
  • 序列相似性Contains 1 C-type lectin domain.
    Contains 1 EGF-like domain.
    Contains 1 Sushi (CCP/SCR) domain.
  • 翻译后修饰O-glycosylated with sialylated oligosaccharides.
    May be N-glycosylated.
  • 细胞定位Membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • CD164 sialomucin like 1 antibody
    • CD164L1 antibody
    • CD248 antibody
    • CD248 antigen endosialin antibody
    • CD248 molecule endosialin antibody
    • CD248_HUMAN antibody
    • Endosialin antibody
    • TEM 1 antibody
    • TEM1 antibody
    • Tumor endothelial marker 1 antibody
    see all

Anti-TEM1 antibody 图像

  • All lanes : Anti-TEM1 antibody (ab48185) at 1 µg/ml

    Lane 1 : Skeletal Muscle (Mouse)
    Lane 2 : Heart (Mouse) Tissue Lysate

    Lysates/proteins at 10 µg per lane.

    Secondary
    Goat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilution

    Performed under reducing conditions.

    Predicted band size : 80 kDa
    Observed band size : 92 kDa (why is the actual band size different from the predicted?)
    Additional bands at : 250 kDa,60 kDa. We are unsure as to the identity of these extra bands.

Anti-TEM1 antibody (ab48185)参考文献

ab48185 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"