• 产品名称Anti-Telethonin抗体
    参阅全部 Telethonin 一抗
  • 描述
    兔多克隆抗体to Telethonin
  • 经测试应用适用于: IHC-P, WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    antigen sequence: CEVSEENCER REAFWAEWKD LTLSTRPEEG CSLHEEDTQR HETYHQQGQC QVLVQRSPWL MMRMGILGRG LPEYQ, corresponding to internal sequence amino acids 8-82 of Human Telethonin.

  • 阳性对照
    • Human heart muscle tissue; Telethonin transfected HEK293T cells.


  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液pH: 7.20
    Preservative: 0.02% Sodium azide
    Constituents: 59% PBS, 40% Glycerol
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 克隆多克隆
  • 同种型IgG
  • 研究领域


Our Abpromise guarantee covers the use of ab121868 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P 1/20 - 1/50. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
WB 1/250 - 1/500.


  • 功能Muscle assembly regulating factor. Mediates the antiparallel assembly of titin (TTN) molecules at the sarcomeric Z-disk.
  • 组织特异性Heart and skeletal muscle.
  • 疾病相关Defects in TCAP are a cause of cardiomyopathy familial hypertrophic (CMH) [MIM:192600]; also designated FHC or HCM. Familial hypertrophic cardiomyopathy is a hereditary heart disorder characterized by ventricular hypertrophy, which is usually asymmetric and often involves the interventricular septum. The symptoms include dyspnea, syncope, collapse, palpitations, and chest pain. They can be readily provoked by exercise. The disorder has inter- and intrafamilial variability ranging from benign to malignant forms with high risk of cardiac failure and sudden cardiac death.
    Defects in TCAP are a cause of limb-girdle muscular dystrophy type 2G (LGMD2G) [MIM:601954]. LGMD2G is an autosomal recessive degenerative myopathy characterized by proximal and distal muscle weakness and atrophy in the limbs, dystrophic changes on muscle biopsy, and absence of telethonin. Cardiac muscle is involved in a subset of patients.
    Defects in TCAP are the cause of cardiomyopathy dilated type 1N (CMD1N) [MIM:607487]. Dilated cardiomyopathy is a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Patients are at risk of premature death.
  • 细胞定位Cytoplasm > myofibril > sarcomere.
  • Information by UniProt
  • 数据库链接
  • 别名
    • 19 kDa sarcomeric protein antibody
    • CMD1N antibody
    • CMH25 antibody
    • LGMD2G antibody
    • Limb girdle muscular dystrophy 2G (autosomal recessive) antibody
    • T-cap antibody
    • Tcap antibody
    • TELE antibody
    • Telethonin antibody
    • TELT_HUMAN antibody
    • Titin cap protein antibody
    • Titin-cap antibody
    see all

Anti-Telethonin antibody 图像

  • ab121868, at 1/45 dilution, staining Telethonin in paraffin-embedded Human heart muscle tissue by Immunohistochemistry.
  • All lanes : Anti-Telethonin antibody (ab121868) at 1/250 dilution

    Lane 1 : Vector only transfected HEK293T lysate
    Lane 2 : Over-expression Lysate (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa) in mammalian HEK293T cells

    Developed using the ECL technique
  • Immunohistochemical staining of Human heart muscle shows distinct cytoplasmic positivity using ab121868

Anti-Telethonin antibody (ab121868)参考文献

ab121868 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab121868.
Please use the links above to contact us or submit feedback about this product.