Anti-TEA domain family member 2抗体(ab92279)

概述

  • 产品名称Anti-TEA domain family member 2抗体
    参阅全部 TEA domain family member 2 一抗
  • 描述
    山羊多克隆抗体to TEA domain family member 2
  • 特异性Not expected to cross-react with other TEA domain family proteins.
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Cow, Dog
  • 免疫原

    Synthetic peptide:

    C-EPPDAVDSYQRH

    , corresponding to internal amino acids 238 - 249 of Human TEA domain family member 2 (NP_003589.1).

  • 阳性对照
    • Human ileum tissue lysate

性能

应用

Our Abpromise guarantee covers the use of ab92279 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
  • 应用说明WB: Use at a concentration of 1 - 3 µg/ml. Detects a band of approximately 50 kDa (predicted molecular weight: 49 kDa).


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Acts by mediating gene expression of YAP1 and WWTR1/TAZ, thereby regulating cell proliferation, migration and epithelial mesenchymal transition (EMT) induction. Binds to the SPH and GT-IIC 'enhansons' (5'-GTGGAATGT-3'). May be involved in the gene regulation of neural development. Binds to the M-CAT motif.
    • 序列相似性Contains 1 TEA DNA-binding domain.
    • 细胞定位Nucleus.
    • Information by UniProt
    • 数据库链接
    • 别名
      • Embryonic TEA domain containing factor antibody
      • Etdf antibody
      • ETEF 1 antibody
      • ETF antibody
      • TEA domain family member 2 antibody
      • TEAD 2 antibody
      • TEAD-2 antibody
      • TEAD2 antibody
      • Tead2 protein (TEA domain family member 2 (Mapped), isoform CRA_b) antibody
      • TEAD2_HUMAN antibody
      • TEF 4 antibody
      • TEF4 antibody
      • Transcriptional enhancer factor 4 antibody
      • Transcriptional enhancer factor TEF 4 antibody
      • Transcriptional enhancer factor TEF-4 antibody
      see all

    Anti-TEA domain family member 2 antibody 图像

    • Anti-TEA domain family member 2 antibody (ab92279) at 1 µg/ml + Human ileum lysate in RIPA buffer at 35 µg
      Developed using the ECL technique

      Predicted band size : 49 kDa
      Observed band size : 50 kDa (why is the actual band size different from the predicted?)

    Anti-TEA domain family member 2 antibody (ab92279)参考文献

    ab92279 has not yet been referenced specifically in any publications.

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